Infection by Mycobacterium caprae in three cattle herds in Emilia-Romagna Region, Northern Italy

Submitted: 3 August 2019
Accepted: 7 January 2020
Published: 6 April 2020
Abstract Views: 1062
PDF: 599
HTML: 27
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Bovine tuberculosis (bTB) is a contagious chronic disease associated with progressive emaciation (starvation) and tubercles (granuloma) formation commonly caused by Mycobacterium bovis. In cattle, M. caprae may also be responsible for bTB. In EU, human tuberculosis due to M. bovis had a notification rate of 0.04 cases per 100,000 inhabitants in 2017, but data did not include M. caprae infections. From September 2018 to April 2019, bTB outbreaks were investigated in three neighbouring dairy cattle herds in Parma province, Northern Italy. Parma municipality belongs to an officially free of bovine tuberculosis (OTF) Italian region. Official testing on cattle herds, performed every three years as legally required, revealed no positive animals. Tubercular lesions were found during the post mortem (PM) examination of slaughtered cattle and M. caprae genotype SB0418/VNTR 4,3,5,3,4,5,2,2,4, 3,15,5 was isolated. This report confirms the crucial importance of PM veterinary inspection at slaughterhouse, despite the OTF status of cattle herds.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Alvarez J, Perez A, Bezos J, Marque´s S, Grau A, Saez JL, Mínguez O, de Juan L, Domínguez L, 2012. Evaluation of the sensitivity and specificity of bovine tuberculosis diagnostic tests in naturally infected cattle herds using a Bayesian approach. Vet Microbiol 155:38–43. DOI: https://doi.org/10.1016/j.vetmic.2011.07.034
Boniotti MB, Goria M, Loda D, Garrone A, Benedetto A, Mondo A, Tisato E, Zanoni M, Zoppi S, Dondo A, Tagliabue S, Bonora S, Zanardi G, Pacciarini ML, 2009. Molecular typing of Mycobacterium bovis strains isolated in Italy from 2000 to 2006 and evaluation of Variable-Number-Tandem-Repeats for a geographic optimized genotyping. J Clin Microbiol 47:636-44. DOI: https://doi.org/10.1128/JCM.01192-08
Boniotti MB, Gaffuri A, Gelmetti D, Tagliabue S, Chiari M, Mangeli A, Spisani M, Nassuato C, Gibelli L, Sacchi C, Zanoni M, Pacciarini ML, 2014. Detection and molecular characterization of Mycobacterium microti in wild boar from Northern Italy. J Clin Microbiol 52: 2834-43. DOI: https://doi.org/10.1128/JCM.00440-14
de la Rua-Domenech R, Goodchild AT, Vordermeier HM, Hewinson RG, Christiansen KH, Clifton-Hadley RS, 2006. Ante mortem diagnosis of tuberculosis in cattle: a review of the tuberculin tests, gamma-interferon assay and other ancillary diagnostic techniques. Res Vet Sci 81:190–210. DOI: https://doi.org/10.1016/j.rvsc.2005.11.005
Domingo M, Vidal E, Marco A, 2014. Pathology of bovine tuberculosis. Research Vet Sci, 97: S20-29. DOI: https://doi.org/10.1016/j.rvsc.2014.03.017
European Food Safety Authority (EFSA), 2012. Scientific Opinion on the use of a gamma interferon test for the diagnosis of bovine tuberculosis. EFSA Journal 10(12):2975. DOI: https://doi.org/10.2903/j.efsa.2012.2975
European Food Safety Authority (EFSA), European Centre for Disease Prevention and Control (ECDC), 2018. The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017. EFSA Journal 16 (12):5500. DOI: https://doi.org/10.2903/j.efsa.2018.5500
Monaghan ML, Doherty ML, Collins JD, Kazda JF, Quinn PJ, 1994. The tuberculin test. Vet Microbiol 40:111–24. DOI: https://doi.org/10.1016/0378-1135(94)90050-7
OIE (World Organization for Animal Health), 2009. Manual of diagnostic tests and vaccines for terrestrial animals. Bovine tuberculosis. Chapter 3.4.6. pp. 1058-74.
OIE (World Organization for Animal Health). Bovine tuberculosis (accessed 06.07.2019)
Perez-Lago L, Navarro Y, Garcìa-de-Viedma D, 2014. Current knowledge and pending challenges in zoonosis caused by Mycobacterium bovis: a review. Res Vet Sci.97: S94-S100. DOI: https://doi.org/10.1016/j.rvsc.2013.11.008
Prodinger WM, Indra A, Koksalan OK, Kilikaslan Z, Richter E, 2014. Mycobacterium caprae infection in humans. Expert Rev Anti Infect Ther 12:1501-13. DOI: https://doi.org/10.1586/14787210.2014.974560

How to Cite

1.
Magnani R, Cavalca M, Pierantoni M, Luppi A, Cantoni AM, Prosperi A, Pacciarini M, Zanoni M, Tamba M, Santi A, Bonardi S. Infection by Mycobacterium caprae in three cattle herds in Emilia-Romagna Region, Northern Italy. Ital J Food Safety [Internet]. 2020 Apr. 6 [cited 2024 Nov. 22];9(1). Available from: https://www.pagepressjournals.org/ijfs/article/view/8467