Clear-cell renal cell carcinoma single thyroid metastasis: A single-center retrospective analysis and review of the literature
Renal cell carcinoma (RCC) is known to cause metastasis to unusual sites, which can be both synchronous or metachronous. Thyroid gland is a rare site for metastasis. However, RCC is the most common primary neoplasm to metastasize to the Thyroid gland. Report of three cases and review of the literature.
Chen H, Nicol TL, Udelsman R. Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg. 1999; 23:177-80.
Willis RA. Metastatic tumours in the thyroid gland. Am J Pathol. 1931; 7:187-208.3.
Bayrakter Z, Albayrak S. Metastasis of renal cell carcinoma to the thyroid gland 9 years after nephrectomy: a case report and literature review. Arch Ital Urol Androl. 2017; 89:151-153.
Cilengir AH, Kalayci TO, Duygulu G, et al. Metastasis of renal clear cell carcinoma to thyroid gland mimicking adenomatous goiter. Pol J Radiol. 2016, 81:618-621.
Motzer RJ, Bander NH, Nanus DM. Renal cell carcinoma. NEJM. 1996. 335:865-875.
Flanigan RC, Campbell SC, Clark JI, et al. Metastatic renal cell carcinoma Curr Treat Options Oncol. 2003;4:385-390.
Eggener SE, Yossepowitch O, Pettus JA, et al. Renal cell carcinoma recurrence after nephrectomy for localized disease: predicting survival from time of recurrence, JCO. 2006; 24:3101-3106.
Aljiabri KS, Bokhari SA, Fadag RB, et al. Thyroid metastasis from renal cell carcinoma, Archives of endocrinology and diabetes care. 2018; 1:65-70.
Chung AY, Tran TB, Brumund KT, et al. Metastases to the tyroid: a review of the literature from the last decade, Thyroid. 2012;22:258-68.
De Stefano R, Carluccio R, Zanni E, et al, Management of thyroid nodules as secondary involvement of renal cell carcinoma case report and literature review, Anticancer research. 2009; 29:473-6.
Khaddour K, Marernych N, Ward WL, et al. Characteristics of clear cell renal cell carcinoma metastases to the thyroid gland: a systematic review, World J Clin Cases. 2019; 7:3474-3485.
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