Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance

  • Roberta Mazzucchelli Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
  • Andrea Benedetto Galosi Division of Urology, “Augusto Murri” General Hospital, ASUR Marche, Fermo, Italy.
  • Antonio Lopez-Beltran Department of Surgery, Cordoba University Medical School, Cordoba, Spain.
  • Marina Scarpelli Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.
  • Liang Cheng Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
  • Rodolfo Montironi | r.montironi@univpm.it Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy.

Abstract

Active surveillance (AS) is an important management option for men with lowrisk, clinically localized prostate cancer. The clinical parameters for patient selection and definition of progression for AS protocols are evolving as data from several large cohorts become mature. Vital to this process is the critical role pathologic parameters play in identifying appropriate candidates for AS. These findings need to be reproducible and accurately reported by pathologists. Repeated biopsy after initial diagnosis of prostate cancer is recommended before inclusion in active surveillance for early detection of significant cancer.

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Published
2014-12-30
Info
Issue
Section
Reviews - Prostate
Keywords:
Prostate cancer, Prostate biopsy, Active surveillance, Tumour extent, Immunohistochemistry
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  • PDF: 538
How to Cite
Mazzucchelli, R., Galosi, A. B., Lopez-Beltran, A., Scarpelli, M., Cheng, L., & Montironi, R. (2014). Pathological issues in biopsy specimens of men with prostate cancer eligible for active surveillance. Archivio Italiano Di Urologia E Andrologia, 86(4), 314-318. https://doi.org/10.4081/aiua.2014.4.314

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