https://doi.org/10.4081/aiua.2023.11101

Safety profile of treatment with greenlight versus Thulium Laser for benign prostatic hyperplasia

Vol. 95 No. 1 (2023)
Submitted: December 19, 2022
Accepted: December 31, 2022
Published: February 22, 2023
Benign Prostatic Hyperplasia, Complications, GreenLight Laser, Learning curve, Safety, Thulium Laser
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Authors

Davide Campobasso
d.campobasso@virgilio.it
https://orcid.org/0000-0003-2072-114X
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla; Department of Urology, University Hospital of Parma, Italy.
Antonio Barbieri
Department of Urology, University Hospital of Parma, Italy.
Tommaso Bocchialini
Department of Urology, University Hospital of Parma, Italy.
Gian Luigi Pozzoli
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Francesco Dinale
Department of Urology, University Hospital of Parma, Italy.
Francesco Facchini
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Marco Serafino Grande
https://orcid.org/0000-0001-5497-4722
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Jean Emmanuel Kwe
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla; Urological Residency School Network, Department of Urology, University Hospital of Modena and Reggio Emilia, Modena, Italy.
Michelangelo Larosa
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Giulio Guarino
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla; Urological Residency School Network, Department of Urology, University Hospital of Modena and Reggio Emilia, Modena, Italy.
Davide Mezzogori
Department of Engineering and Architecture, University of Parma, Italy.
Elisa Simonetti
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Francesco Ziglioli
https://orcid.org/0000-0002-3066-9798
Department of Urology, University Hospital of Parma, Italy.
Antonio Frattini
Department of Urology, Ospedale Civile di Guastalla and Ospedale Ercole Franchini di Montecchio Emilia, Guastalla, Italy.
Umberto Vittorio Maestroni
Department of Urology, University Hospital of Parma, Italy.

Objective: The major strengths of surgical treatment of benign prostatic hyperplasia with laser are reduced morbidity compared to endoscopic resection. No studies analysed the different risk of intra/peri-operative events between patients undergoing Thulium and GreenLight procedures.

Materials and methods: We retrospectively reviewed 100 consecutive cases undergoing GreenLight vaporization and Thulium procedures performed during the learning curve of two expert endoscopic surgeons. Pre-operative data, intra and post-operative events at 90 days were analysed.

Results: Patients on antiplatelet/anticoagulant therapy were pre-dominant in the Green group (p < 0.0001). Rates of blood transfusion (p < 0.0038), use of resectoscope (p < 0.0086), and transient stress urinary incontinence were statistically higher in the Thulium group. On the contrary conversions to TURP (p < 0.023) were more frequent in GreenLight patients. Readmissions were more frequently necessary in GreenLight group (24%) vs. Thulium group (26.6%). The overall complication rate in GreenLight and Thulium groups were 31% and 53% respectively; Clavien 3b complications were 13% in Thulium patients versus 1% in GreenLight patients.

Conclusions: GreenLight and Thulium treatments show similar safety profiles. Randomized controlled trial are needed to better clarify the rate of major complications in Thulium group, and the incidence of post-operative storage symptoms in these patients’ populations.

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How to Cite

Campobasso, D., Barbieri, A., Bocchialini, T., Pozzoli, G. L., Dinale, F., Facchini, F., Grande, M. S., Kwe, J. E., Larosa, M., Guarino, G., Mezzogori, D., Simonetti, E., Ziglioli, F., Frattini, A., & Maestroni, U. V. (2023). Safety profile of treatment with greenlight versus Thulium Laser for benign prostatic hyperplasia. Archivio Italiano Di Urologia E Andrologia, 95(1). https://doi.org/10.4081/aiua.2023.11101
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