https://doi.org/10.4081/aiua.2022.1.126
Overweight and obesity: The allies of prostate inflammation
Submitted: February 14, 2022
Accepted: February 17, 2022
Published: March 30, 2022
Accepted: February 17, 2022
Abstract Views: 865
PDF: 506
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
To the Editor,
World Health Organization (WHO) defines infertility as the inability of a sexually active partner to achieve a clinically confirmed pregnancy after at least one year of intercourse without contraceptive protection on fertile days. As women are primarily responsible for the conception, childbirth, and postpartum, fertility problems have been related to fertile female capacity. However, men play an essential role, being responsible for about 50% of alterations in fertility due to dysfunctions in the male reproductive tract, including varicocele, hypogonadism, poorly descended testicles, testicular tumors, and even anti-sperm autoantibodies [...].
Zegers-Hochschild F, Adamson GD, de Mouzon J, et al. The International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) Revised Glossary on ART Terminology, 2009. Hum Reprod. 2009; 24:2683.
DOI: https://doi.org/10.1093/humrep/dep343
Jungwirth A, Giwercman A, Tournaye H, et al. European Association of Urology Guidelines on Male Infertility: The 2012 Update. Eur Urol. 2012; 62:324.
DOI: https://doi.org/10.1016/j.eururo.2012.04.048
Restrepo B, Cardona Maya W. Anticuerpos antiespermatozoides y su asociación con la fertilidad. Actas Urol Esp 2013; 37:571.
DOI: https://doi.org/10.1016/j.acuro.2012.11.003
Mayorga-Torres BJ, Camargo M, Agarwal A, et al. Influence of ejaculation frequency on seminal parameters. Reprod Biol Endocrinol. 2015; 13:47.
DOI: https://doi.org/10.1186/s12958-015-0045-9
Barazani Y, Katz BF, Nagler HM, Stember DS. Lifestyle, environment, and male reproductive health. Urol Clin North Am. 2014; 41:55.
DOI: https://doi.org/10.1016/j.ucl.2013.08.017
Wise LA, Cramer DW, Hornstein MD, et al. Physical activity and semen quality among men attending an infertility clinic. Fertil Steril. 2011;95:1025.
DOI: https://doi.org/10.1016/j.fertnstert.2010.11.006
Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during past 50 years. BMJ. 1992; 305:609.
DOI: https://doi.org/10.1136/bmj.305.6854.609
Condorelli RA, Russo GI, Calogero AE, et al. Chronic prostatitis and its detrimental impact on sperm parameters: a systematic review and meta-analysis. J Endocrinol Invest. 2017; 40:1209.
DOI: https://doi.org/10.1007/s40618-017-0684-0
Williams DHt, Karpman E, Sander JC, et al. Pretreatment semen parameters in men with cancer. J Urol. 2009; 181:736.
DOI: https://doi.org/10.1016/j.juro.2008.10.023
Chavarro JE, Toth TL, Wright DL, et al. Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic. Fertil Steril. 2010; 93:2222.
DOI: https://doi.org/10.1016/j.fertnstert.2009.01.100
Krieger JN, Lee SW, Jeon J, et al. Epidemiology of prostatitis. Int J Antimicrob Agents. 2008; 31 Suppl 1:S85.
DOI: https://doi.org/10.1016/j.ijantimicag.2007.08.028
Sallmen M, Sandler DP, Hoppin JA, Blair A, Baird DD. Reduced fertility among overweight and obese men. Epidemiology. 2006; 17:520.
DOI: https://doi.org/10.1097/01.ede.0000229953.76862.e5
Cabler S, Agarwal A, Flint M, du Plessis SS. Obesity: modern man's fertility nemesis. Asian J Androl. 2010; 12:480.
DOI: https://doi.org/10.1038/aja.2010.38
Wallner LP, Clemens JQ, Sarma AV. Prevalence of and risk factors for prostatitis in African American men: The Flint Men's Health Study. Prostate. 2009; 69:24-32.
DOI: https://doi.org/10.1002/pros.20846
Parikesit D, Mochtar CA, Umbas R, Hamid AR. The impact of obesity towards prostate diseases. Prostate Int. 2016; 4:1.
DOI: https://doi.org/10.1016/j.prnil.2015.08.001
Parazzini F, Artibani W, Carrieri G, et al. Effect of body mass and physical activity at younger age on the risk of prostatic enlargement and erectile dysfunction: Results from the 2018# Controllati survey. Arch Ital Urol Androl 2019; 91:245.
DOI: https://doi.org/10.4081/aiua.2019.4.245
Roth MY, Amory JK, Page ST. Treatment of male infertility secondary to morbid obesity. Nat Clin Pract Endocrinol Metab. 2008; 4:415.
DOI: https://doi.org/10.1038/ncpendmet0844
Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc. 2001;60:329.
DOI: https://doi.org/10.1079/PNS200194
Bhat GK, Sea TL, Olatinwo MO, et al. Influence of a leptin deficiency on testicular morphology, germ cell apoptosis, and expression levels of apoptosis-related genes in the mouse. J Androl. 2006; 27:302.
DOI: https://doi.org/10.2164/jandrol.05133
Isidori AM, Caprio M, Strollo F, et al. Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels. J Clin Endocrinol Metab. 1999; 84:3673.
DOI: https://doi.org/10.1210/jcem.84.10.6082
Tewari R, Rajender S, Natu SM, et al. Diet, obesity, and prostate health: are we missing the link? J Androl. 2012; 33:763.
DOI: https://doi.org/10.2164/jandrol.111.015578
Bialas M, Fiszer D, Rozwadowska N, et al. The role of IL-6, IL-10, TNF-alpha and its receptors TNFR1 and TNFR2 in the local regulatory system of normal and impaired human spermatogenesis. Am J Reprod Immunol. 2009; 62:51.
DOI: https://doi.org/10.1111/j.1600-0897.2009.00711.x
Fraczek M, Kurpisz M. Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa. J Androl. 2007; 28:325-33.
DOI: https://doi.org/10.2164/jandrol.106.001149
Agarwal A, Sharma RK, Nallella KP, et al. Reactive oxygen species as an independent marker of male factor infertility. Fertil Steril. 2006;86:878.
DOI: https://doi.org/10.1016/j.fertnstert.2006.02.111
Mayorga-Torres BJM, Camargo M, Cadavid AP, et al. Are oxidative stress markers associated with unexplained male infertility? Andrologia. 2017; 49.
DOI: https://doi.org/10.1111/and.12659
Agarwal A, Rana M, Qiu E, et al. Role of oxidative stress, infection and inflammation in male infertility. Andrologia. 2018; 50:e13126.
DOI: https://doi.org/10.1111/and.13126
Ross C, Morriss A, Khairy M, et al. A systematic review of the effect of oral antioxidants on male infertility. Reproductive BioMedicine Online. 2010; 20:711.
DOI: https://doi.org/10.1016/j.rbmo.2010.03.008
Benatta M, Kettache R, Buchholz N, Trinchieri A. The impact of nutrition and lifestyle on male fertility. Arch Ital Urol Androl 2020; 92:121.
DOI: https://doi.org/10.4081/aiua.2020.2.121
Agarwal A, Saleh RA, Bedaiwy MA. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril. 2003; 79:829.
DOI: https://doi.org/10.1016/S0015-0282(02)04948-8
Ihsan AU, Khan FU, Khongorzul P, et al. Role of oxidative stress in pathology of chronic prostatitis/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress. Biomed Pharmacother. 2018; 106:714.
DOI: https://doi.org/10.1016/j.biopha.2018.06.139
How to Cite
Moncada López, J. S. ., Puerta Suárez, J., & Cardona Maya, W. D. (2022). Overweight and obesity: The allies of prostate inflammation. Archivio Italiano Di Urologia E Andrologia, 94(1), 126–128. https://doi.org/10.4081/aiua.2022.1.126
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.