https://doi.org/10.4081/aiua.2024.12894

Correlation between histopathology properties of dartos tissue and the severity of penile curvature in hypospadias

Vol. 96 No. 4 (2024)
Submitted: August 2, 2024
Accepted: October 12, 2024
Published: December 18, 2024
Hypospadias, chordee, penile curvature, collagen, fibrotic
Abstract Views: 2
PDF: 1
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Authors

Gede Wirya Kusuma Duarsa
gwkurology@gmail.com
Department of Urology, Faculty of Medicine Universitas Udayana/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Pande Made Wisnu Tirtayasa
Department of Urology, Faculty of Medicine Universitas Udayana/Universitas Udayana Teaching Hospital, Denpasar, Indonesia.
Ni Wayan Winarti
https://orcid.org/0000-0002-4778-4848
Department of Pathology Anatomy, Faculty of Medicine Universitas Udayana/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Andy Michael
Department of Surgery, Faculty of Medicine Universitas Udayana/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Indonesia.
Komang Harsa Abhinaya Duarsa
Medical Doctor Study Program, Faculty of Medicine Universitas Udayana, Denpasar, Indonesia.

Purpose: Hypospadias, one of the congenital anomalies commonly associated with some degrees of ventral penile curvature that may arise from malformation of dartos fascia, the chordee. Our study aims to determine the correlation between the histopathology properties of dartos fascia and the severity of ventral penile curvature in hypospadias.

Materials and methods: One hundred hypospadias patients with various degrees of ventral penile curvature were included in this cross-sectional analytical study from 2020 to 2022. During hypospadias repair, ventral dartos fascia was excised and analyzed for the degree of collagen thickness and the severity of the fibrotic condition.

Results: Out of 100 patients, the mean age was 6.58 + 4.28 years, who were classified as mild to moderate (66%) and severe (34%) ventral curvature cases. The analyses showed significant differences in the severity of fibrotic condition and collagen thickness of dartos fascia to the severity of penile ventral curvature with p-values of 0.002 and 0.017, respectively.

Conclusions: The difference in histopathology properties of dartos fascia may affect the severity of penile curvature in hypospadias patients.

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How to Cite

Duarsa, G. W. K., Tirtayasa, P. M. W., Winarti, N. W., Michael, A., & Duarsa, K. H. A. (2024). Correlation between histopathology properties of dartos tissue and the severity of penile curvature in hypospadias. Archivio Italiano Di Urologia E Andrologia, 96(4). https://doi.org/10.4081/aiua.2024.12894
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