A systematic review and meta-analysis of short- and long-term complications of early versus delayed penile prosthesis implantation in patients with ischemic priapism

Published: October 2, 2024
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Background: This study determined pooled estimates of short- and long-term complications of early versus delayed implantation of penile prosthesis in patients with ischemic priapism.
Methods: We searched Pubmed, ProQuest, Scopus, EBSCOHost, and other sources from January 1, 2013, to March 2023. All study designs were included except animal studies, review articles, and consensus documents. Of the 214 articles, four studies were included in the systematic review, and further meta-analysis included three studies (PROSPERO CRD42023411005).
Results: The short-term complication rate was lower with early implantation than with later implantation (β= -2.08; 95% Confidence Interval [CI] = -3.54, -0.6; p = < 0.05). A similar value was also found in the pooled analysis for long-term outcomes, defined as overall satisfaction rate, which is better with early implantation than later (β = 2.18; 95% CI = 1.35, 3.02; p= < 0.05).
Conclusions: The results of the pooled analysis confirmed that short-term complications were significantly lower with early implantation than with delayed implantation. Overall satisfaction rates were higher in early implantation than in delayed implantation of penile prostheses.

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Mishra K, Loeb A, Bukavina L, et al. Management of priapism: a contemporary review. Sex Med Rev 2020; 8:131-9.
Biebel MG, Gross MS, Munarriz R. Review of Ischemic and Nonischemic Priapism. Curr Urol Rep. 2022; 23:143-53.
Bivalacqua TJ, Allen BK, Brock G, et al. Acute ischemic priapism: An AUA/SMSNA Guideline. J Urol 2021; 206:1114-21.
Ericson C, Baird B, Broderick GA. Management of priapism: 2021 Update. Urol Clin North Am 2021; 48:565-76.
Yücel ÖB, Pazır Y, Kadıoglu A. Penile prosthesis implantation in priapism. Sex Med Rev 2018; 6:310-8.
Reddy A, Finley L, Horrall S. Hyperosmolar hyperglycemic syndrome in a young boy. Proc (Bayl Univ Med Cent) 2019;32:627-628.
Zacharakis E, Garaffa G, Raheem AA, et al. Penile prosthesis insertion in patients with refractory ischaemic priapism: early vs delayed implantation. BJU Int 2014; 114:576-81.
Salem EA, El Aasser O. Management of ischemic priapism bypenile prosthesis insertion: prevention of distal erosion. J Urol 2010;183:2300-3.
Tausch TJ, Zhao LC, Morey AF, et al. Malleable penile prosthesis is a cost-effective treatment for refractory ischemic priapism. J Sex Med 2015;12:824-6.
Joice GA, Liu JL, Burnett AL. Medical treatment of recurrent ischaemic priapism: a review of current molecular therapeutics and a new clinical management paradigm. BJU Int 2021;127:498-506.
Reddy AG, Alzweri LM, Gabrielson AT, et al. Role of penile prosthesis in priapism: A review. World J Mens Health 2018;36:4.
Salman B, Elsherif E, Elgharabawy M, Badawy A. Early versus delayed penile prosthesis insertion for refractory ischemic priapism. Arab J Urol. 2022;21:76-81.
Rees RW, Kalsi J, Minhas S, et al. The management of low-flow priapism with the immediate insertion of a penile prosthesis. BJU Int. 2002;90:893-7.
Muneer A, Ralph DJ. Immediate placement of a penile prosthesis as first-line treatment for the management of ischaemic priapism. Eur Urol Focus 2019;5:529-30.
Ha AS, Han DS, Wallace BK, et al. A population-based analysis o
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. Syst Rev 2021;10:1-11.
De Niro AJN, Kusuma Duarsa GW, Yudiana IW, et al. Penile prosthesis implantation in priapism: is early indicating better outcomes? PROSPERO 2023-CRD42023411005. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=411005
Krzastek SC, Smith R. An update on the best approaches to prevent complications in penile prosthesis recipients. Ther Adv Urol 2019; 11:1756287218818076.
Palmisano F, Vagnoni V, Franceschelli A, et al. Immediate insertion of a soft penile prosthesis as a new option for a safe and costeffective treatment of refractory ischemic priapism. Arch Ital Urol Androl 2021;93:356-60.
Capece M, Falcone M, Cai T, et al. Penile prosthesis implantation in refractory ischaemic priapism: patient selection and special considerations. Res Rep Urol 2022;14:1-6.
Moore J, Whelan TF, Langille GM. The use of penile prostheses in the management of priapism. Transl Androl Urol 2017;6:S797-803.
Yafi FA, Hellstrom WJG. Immediate placement of penile prosthesis for the management of ischemic priapism as first-line treatment. Eur Urol Focus 2019;5:531-2.
Krughoff K, Bearelly P, Apoj M, et al. Multicenter surgical outcomes of penile prosthesis placement in patients with corporal fibrosis and review of the literature. Int J Impot Res 2022;34:86-92.
Hebert KL, Yafi FA, Wilson S. Inflatable penile prosthesis implantation into scarred corporal bodies: timing may decrease postoperative problems. BJU Int 2020;125:168-72.
Sedigh O, Rolle L, Negro CLA, et al. Early insertion of inflatable prosthesis for intractable ischemic priapism: our experience and review of the literature. Int J Impot Res 2011;23:158-64.
Johnson M, Hallerstrom M, Chiriaco G, et al. PD44-01 A comparison between early and delayed penile prosthesis insertion in men with refractory ischaemic priapism. J Urol 2019;201:e821.
Elhawy MM, Fawzy AM. Outcomes of low-flow priapism and role of integrated penile prosthesis management. Afr J Urol. 2021;27:1-8.

How to Cite

Nanda De Niro, A. J., Duarsa, G. W. K., Harvy Wicaksono, M., Tirtayasa, P. M. W., Santosa, K. B., Yudiana, I. W., & Prayudi, N. G. (2024). A systematic review and meta-analysis of short- and long-term complications of early versus delayed penile prosthesis implantation in patients with ischemic priapism. Archivio Italiano Di Urologia E Andrologia, 96(3). https://doi.org/10.4081/aiua.2024.12576