Iron homeostasis alterations and erectile dysfunction: A new issue in erectile disfunction treatment?
Published: February 16, 2024
Abstract Views: 357
PDF: 210
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso; Department of Urology, Humanitas Gavazzeni, Bergamo, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
Department of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, Naples, Italy.
To the Editor,
Erectile dysfunction (ED) is one of the most prevalent conditions affecting men globally, with significant psychological and social consequences. The prevalence varies across different populations, and it is estimated around 50% in men aged between 40 to 70. The etiology of ED is multifactorial, involving a complex crosstalk between psychological, hormonal, neurogenic, vascular, and structural factors [...]
Mirone V, Napolitano L, D'Emmanuele di Villa Bianca R, et al. A new original nutraceutical formulation ameliorates the effect of Tadalafil on clinical score and cGMP accumulation. Arch Ital Urol Androl 2021;93:221-6.
DOI: https://doi.org/10.4081/aiua.2021.2.221
Napolitano L, Fusco GM, Cirillo L, et al. Erectile dysfunction and mobile phone applications: Quality, content and adherence to European Association guidelines on male sexual dysfunction. Arch Ital Urol Androl 2022;94:211-6.
DOI: https://doi.org/10.4081/aiua.2022.2.211
Feldman HA, Goldstein I, Hatzichristou DG, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61.
DOI: https://doi.org/10.1016/S0022-5347(17)34871-1
Cirillo L, Fusco GM, Di Bello F, et al. Sexual dysfunction: Time for a multidisciplinary approach? Arch Ital Urol Androl 2023;95:11236.
DOI: https://doi.org/10.4081/aiua.2023.11236
Shamloul R, Ghanem H. Erectile dysfunction. Lancet 2013;381:153-65.
DOI: https://doi.org/10.1016/S0140-6736(12)60520-0
Camaschella C. Iron-deficiency anemia. N Engl J Med 2015;372:1832-43.
DOI: https://doi.org/10.1056/NEJMra1401038
Brissot P, Ropert M, Le Lan C, Loréal O. Non-transferrin bound iron: a key role in iron overload and iron toxicity. Biochim Biophys Acta 2012;1820:403-10.
DOI: https://doi.org/10.1016/j.bbagen.2011.07.014
Barton JC, McDonnell SM, Adams PC, et al. Management of hemochromatosis. Hemochromatosis Management Working Group. Ann Intern Med 1998;129:932-9.
DOI: https://doi.org/10.7326/0003-4819-129-11_Part_2-199812011-00003
Choi JW, Pai SH, Kim SK, et al. Iron deficiency anemia increases nitric oxide production in healthy adolescents. Ann Hematol 2002;81:1-6.
DOI: https://doi.org/10.1007/s00277-001-0409-4
Darbandi M, Darbandi S, Agarwal A, et al. Reactive oxygen species and male reproductive hormones. Reprod Biol Endocrinol 2018;16:87.
DOI: https://doi.org/10.1186/s12958-018-0406-2
Atli G, Canli M. Response of antioxidant system of freshwater fish Oreochromis niloticus to acute and chronic metal (Cd, Cu, Cr, Zn, Fe) exposures. Ecotoxicol Environ Saf 2010;73:1884-9.
DOI: https://doi.org/10.1016/j.ecoenv.2010.09.005
Simonsen U, Rodriguez-Rodriguez R, Dalsgaard T, et al. Novel approaches to improving endothelium-dependent nitric oxide mediated vasodilatation. Pharmacol Rep 2009;61:105-15.
DOI: https://doi.org/10.1016/S1734-1140(09)70012-X
He H, Qiao Y, Zhou Q, et al. Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway. Oxid Med Cell Longev 2019;2019:2340392.
DOI: https://doi.org/10.1155/2019/2340392
How to Cite
Marino, C., Iaconis, S., Di Bello, F., Cacace, G., Fusco, G., Romano, L., Di Mauro, E., Cirillo, L., Altieri, V. M., Mastrangelo, F., Napolitano, L., & Palmieri, A. (2024). Iron homeostasis alterations and erectile dysfunction: A new issue in erectile disfunction treatment?. Archivio Italiano Di Urologia E Andrologia, 96(1). https://doi.org/10.4081/aiua.2024.12245
Copyright (c) 2024 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.