Complex Decongestive Therapy in lymphedema: report from an Interdisciplinary Center

Submitted: 28 June 2023
Accepted: 9 August 2023
Published: 23 August 2023
Abstract Views: 1358
PDF: 93
SUPPLEMENTARY PDF: 27
HTML: 10
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Lymphedema is a chronic and worsening disease due to an abnormal accumulation of liquids, with a high protein content in the interstitial space. The disease is characterized by an insufficient flow of lymphatic fluid, which manifests as edema, inflammation, and fibrosis, all the way up to the stiffening of the affected tissues. Because it’s a chronic and increasing disease, the treatment is highly complex. The literature shows that the treatment must be multidisciplinary, and it is necessary to combine multiple techniques, such as manual lymphatic drainage, mechanical lymphatic drainage, elasto-compressive bandages, and other complementary techniques up to surgical treatment in the most advanced forms which are not responsive to physical therapy. Furthermore, the disease is characterized by episodes of cellulitis, that may lead to infectious complications because the lymphatic function becomes insufficient. A condition of local immunodeficiency is created due to the crucial role that the lymphatic system covers with immune defenses, therefore creating a fertile ground for infections caused by small skin wounds, insect bites, animal scratches, nail fungus, and blood draws. Therefore, particular attention is paid to skin folds and interdigital spaces for which hygiene is necessary by using neutral detergents, drying by dabbing, and applying emollient creams for skin hydration. Unfortunately, such practices of prevention and care are often underestimated. We provide education to the patient on self-care, such as the self-bandage and the correct application of the elastocompressed stoking. For wrapping the bandage, it is advisable to wear a glove or a special sock. The multilayer bandages are used in the first decongestant phase, while over time, the elastic stocking is the best aid for the management of lymphedema. Our clinic is a referral center for diagnosis, treatment, and surgical therapy, where patients come for surgical evaluation. Since 2016, we have systematically collected clinical data and volume evaluation of more than 600 cases affected by lymphedema and lipoedema of all stages. They have been treated with complex decongestive therapy for 4 hours a day, 15 consecutive days, subsequently maintenance once a week for 3 months, then once a month for 6 months. Of more than 600 patients treated, only 150 were submitted to surgery (lymphatic venous anastomosis, fasciotomy or liposuction, chylothorax and chyloperitoneal shunt, reconstructive plastic of external genitalia). Complex decongestive interdisciplinary therapy, when properly performed, can stabilize the lymphedema patient situation, reducing the stage and ensuring a good quality of life.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Becker C, Arrive L, Saaristo A, et al. Surgical treatment of congenital lymphedema. Clin Plast Surg. 2012;39:377-84. DOI: https://doi.org/10.1016/j.cps.2012.08.001
Benda K, Lebloch D, Bendova M. Prevention of primary lymphedema-possible way. Lymphology. 1998;31:465-8.
Bernard P. Primary and secondary hospitalization criteria. Ann Dermatol Venereol. 2001; 128:363-7.
Boccardo F, et al. A Pilot. Study of prevention of secondary lymphedema. Lymphology 2000:33:222-555.
Boccardo F, Bellini C, Eretta C, et al. The lymphatics in the pathophysiology of thoracic and abdominal surgical pathology: immunological consequences and the unexpected role of microsurgery. Microsurgery. 2007;27:339-45. DOI: https://doi.org/10.1002/micr.20347
Heal D. Improving patient concordance in lymphoedema management with SoftFit techonology. Br J Community Nurs. 2017;22:S22-7. DOI: https://doi.org/10.12968/bjcn.2017.22.Sup5.S22
Bruna J. Indication for lymphography in the era of new imaging methods. Lymphology. 1994;27:319-20.
Bonnetblanc JM, Bedane C. Erysipelas: recognition and management. Am J Clin Dermatol. 2003;4:157-63. DOI: https://doi.org/10.2165/00128071-200304030-00002
BA Corliss, MSAzimi, J Munson,et al. Macrophages: An inflammatory link between Angiogenesis and Lymphangiogenesis. Microcirculation. 2016;23:95-121. DOI: https://doi.org/10.1111/micc.12259
Campisi C, Bellini C, Eretta C, et al. Diagnosis and management of primary chylous ascites. J Vasc Surg. 2006;43. DOI: https://doi.org/10.1016/j.jvs.2005.11.064
Campisi C, Davini D, Bellini C, et al. Lymphatic microsurgery for the treatment of lymphedema. Microsurgery. 2006;26:65-9. DOI: https://doi.org/10.1002/micr.20214
Campisi C, Davini D, Bellini C, et al. Is there a role for microsurgery in the prevention of arm lymphedema secondary to breast cancer treatment? Microsurgery. 2006;26_70-2. DOI: https://doi.org/10.1002/micr.20215
Campisi C, Eretta C, Pertile D, et al. Microsurgery for treatment of peripheral lymphedema: long-term outcome and future perspectives. Microsurgery. 2007;27:333-8. DOI: https://doi.org/10.1002/micr.20346
Campisi C, Zilli A, Macciò A, et al. La prevenzione del linfedema secondario al trattamento del tumore della mammella: dal caso clinico ad una proposta di protocollo di prevenzione. Chir Ital. 2004;56:419-24.
Cooper G.Compression of therapy and the management of lower-limb lymphoedema: the male perspective. Br J Community Nurs. 2015;20:122-4. DOI: https://doi.org/10.12968/bjcn.2015.20.3.118
De Godoy JM, De Godoy MF, Valente A, et al. Lymphoscintigraphic evaluation in patients after erysipelas. Lymphology 2000;33:177-80.
Dupuy A, Benchikhi H, Roujeau JC, et al. Risk factors for erysipelas of the leg (cellulitis): case-control study. BMJ. 1999;318:1591-4. DOI: https://doi.org/10.1136/bmj.318.7198.1591
Eretta C, Ferrarese A, Moggia E, et al. Surgical treatment of recidivist lymphedema. Open Med (Wars). 2016;11:121-4. DOI: https://doi.org/10.1515/med-2016-0023
Executive Commitee of the international Society of Lymphology, The diagnosis and treatment of peripheral lymphedema: 2020 Consensus Document of the International Society of Lymphology. Lymphology. 2020;53:3-19. DOI: https://doi.org/10.2458/lymph.4649
Földi E. Therapy of lymphedema. Hautarzt. 2012;63:627-33. DOI: https://doi.org/10.1007/s00105-012-2364-5
Földi M. The therapy of lymphedema. European Journal of Lymphology and related problems. 1993-1994;14:43-9.
Franz-Josef Schingale. Compliance improvement of compression therapy inpatients with lymphedema. Veins and Lymphatics 2018;7:7635. DOI: https://doi.org/10.4081/vl.2018.7635
G. Bonetti, K. Dhuli, S. Michelini, et al. Dietary supplements in lymphedema, 2022;63.
Honnor A. Understanding the management of lymphoedema for patients with advanced disease. Int J Palliat Nurs. 2009;15:166-9. DOI: https://doi.org/10.12968/ijpn.2009.15.4.41961
International Society of Lymphology Executive Committee. The Diagnosis and Treatment of Peripheral Lymphedema. Lymphology. 1995;28.
International Congress of Lymphology, Chennai, India. General Assembly ISL Consensus Document Revisited. 1999.
ISL Executive Committee Meeting, Földi Klinik, Hinterzarten, Germany. Discussions on modification of the ISL Consensus Document.
Ishida O et al. Evaluation of lymphatic and non lymphatic edema by MRI. In progress in: Lymphology XIII, Ed.EV Cluzan. Elsevier Sc. Publisher,1992.
Kano Y, Inaoka M, Shiohara T. Superficial lymphangitis with interface dermatitis occurring shortly after a minor injury: possible involvement of a bacterial infection and contact allergens. Dermatology 2001;203:217-20. DOI: https://doi.org/10.1159/000051752
Lasinski BB; Complete decongestive therapy for treatment of lymphedema. Semin Oncol Nurs 2013:29:20-7. DOI: https://doi.org/10.1016/j.soncn.2012.11.004
Leduc A. Le drainage lymphatique.7th ed. Paris, France, Masson. 1991.
Leduc A, Bourgeois P, Bastin R. Lymphatic reabsorption of proteins and pressotherapies. V Congrès du Group Européen de Lymphologie (GEL) Porto, Portugal. 1985.
ML Lanzi. Pedagogia Sociale Manuale per l’infermiere, Carocci Faber. 2004.
Mancini S; Trattato di Flebologia e Linfologia. UTET. 2001.
Marzanna T. Zaleska, Waldemar L. Olszewski, Mariusz K. Kaczmarek. Optimal intermittent pneumat-ic compression in lymphedema. Veins and Lymphatics 2018;7:7985. DOI: https://doi.org/10.4081/vl.2018.7985
Michelini S, Caldirola R, Forner Cordero I, et al. “Linforoll: A new device for treatment of lymphedema. Preliminary experience” Eur J Lymph. 2013;24-25.
Michelini S, Paolacci S, Manara E, et al. Genetic tests in lymphatic vascular malformations and lymphedema. J Med Genet. 2018;55:222-32. DOI: https://doi.org/10.1136/jmedgenet-2017-105064
Mihara M, Hara H, Kikuchi, et al. Scarless lymphatic venous anastomosis for latent and early-stage lymphoedema using indocyanine green lymphography and non-invasive instruments for visualising subcutaneous vein. J Plast Reconstr Aesthet Surg. 2012:65. DOI: https://doi.org/10.1016/j.bjps.2012.05.026
Mihara M, Murai N, Hayashi Y, et al. Using indocyanine green fluorescent lymphography and lymhatic venous anastomosis for cancer related lymphedema. Ann Vasc Surg. 2012;26:278.e1-6. DOI: https://doi.org/10.1016/j.avsg.2011.08.007
The Diagnosis and Treatment of Peripheral Lymphedema: 2009 Consensus Document of the International Society of Lymphology. Lymphology. 2009;42.
The Diagnosis and Treatment of Peripheral Lymphedema: 2013 Consensus Document of the International Society of Lymphology. Lymphology. 2013;46.
Thomson M, Walker J. Collaborative lymphoedema management:developing a clinical. Int J Palliat Nurs. 2011;17:231-8. DOI: https://doi.org/10.12968/ijpn.2011.17.5.231
Uhara H, Saida T, Watanabe T, Takizawa Y. Lymphangitis of the foot demonstrating lymphatic drainage pathways from the sole. J Am Acad Dermatol. 2002;47:502-4. DOI: https://doi.org/10.1067/mjd.2002.122754
Vaillant L. Diagnostic criteria for erysipelas. Ann Dermatol Venereol. 2001;128:326-33.
Waldemar L. Olszewski, Marzanna Zaleska, Marta Cakala. Lymphedema is more than excess of fluid; a lympho-fibro-adipo-edema. Veins and Lymphatics 2018;7:7984 DOI: https://doi.org/10.4081/vl.2018.7984

How to Cite

Eretta, C., Tridoni, E., Isaia, S., Pigoni, A., Vatteroni, A., Impieri, L., & Bianchi, C. (2023). Complex Decongestive Therapy in lymphedema: report from an Interdisciplinary Center. Veins and Lymphatics, 12(1). https://doi.org/10.4081/vl.2023.11551