The role of ozone in the treatment of the acute phase of ischemic heart disease

The present paper describes the role of ozone in the treatment of the acute phase of ischemic heart disease. Two studies are presented: the first mechanically induced myocardial ischemia in rats; the second involved 42 consecutive patients with an outcome comparable to the UA/non-Q wave NSTEMI AMI group of the ENACT study, divided randomly into 2 groups with homogeneous quantitative levels (NYHA class II-III) and was evaluated at weeks 8 and 12 of treatment with ozone. Both studies confirm that i) the effectiveness of ozone therapy increases in relation to how early and how long treatment is performed; and ii) that ozone reduces the relative risk both of ischemic (infarct extension) and arrhythmia complications.