https://doi.org/10.4081/mm.2017.6977

Rapid detection of cryptococcal antigen by a flow assay

Vol. 32 No. 3 (2017)
Submitted: 4 August 2017
Accepted: 5 September 2017
Published: 10 October 2017
Cryptococcosis, antigen, LFA
Abstract Views: 1022
PDF: 714
HTML: 246
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Graziano Bargiggia
Microbiology and Virology Laboratory, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Silvia Corbellini
Microbiology and Virology Laboratory, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Gaia Ortalli
Microbiology and Virology Laboratory, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Fausto Moioli
Microbiology and Virology Laboratory, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Claudio Farina
cfarina@asst-pg23.it
http://orcid.org/0000-0003-2298-4293
Microbiology and Virology Laboratory, Papa Giovanni XXIII Hospital, Bergamo, Italy.
Cryptococcosis is a life-threatening infection caused by Cryptococcus neoformans and C. gattii. Tests for quick detection of the cryptococcal antigen are needed. This study compares the performance of a lateral flow assay (LFA) to the latex agglutination method. Thirty-five cryopreserved positive samples (sera and cerebrospinal fluids) plus three negative sera for control have been examined. LFA does not need high-temperature incubation or enzyme pre-treatment. All the results, except for one serum, agree with previous obtained with latex agglutination method. LFA has an important clinical utility for its rapidity and sensitivity, and it also can be used as a point-of-care test.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

Crossref
Scopus
Google Scholar
Europe PMC

How to Cite

Bargiggia, G., Corbellini, S., Ortalli, G., Moioli, F., & Farina, C. (2017). Rapid detection of cryptococcal antigen by a flow assay. Microbiologia Medica, 32(3). https://doi.org/10.4081/mm.2017.6977

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.