A fatal rhabdomyolysis with the presence of Bacillus cereus on blood culture: description of a clinical case
https://doi.org/10.4081/mm.2024.12419
Accepted: 2 April 2024
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Bacillus cereus is a Gram-positive bacterium that is ubiquitously present. It is often involved in gastrointestinal infections and food poisoning, but it can rarely cause serious non-gastrointestinal tract infections, particularly in immunocompromised individuals. The pathogenicity of B. cereus is predominantly derived from the production of tissue-destructive exoenzymes, including hemolysins, phospholipases, and proteases. Here, we present a case of bacteremia due to B. cereus in an elderly patient, admitted to the emergency room for respiratory failure and rhabdomyolysis after a fall. The microorganism was detected through blood culture and identified using the MALDI-TOF technique. Despite the rapid start of antibiotic therapy, laboratory data have highlighted how this bacterium, through its virulence factors, can be lethal in the case of rhabdomyolysis, worsening the inflammatory response and subverting the host-microorganism relationship in its favor.
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