Dermal ultrastructure in a case of Parry-Romberg syndrome
https://doi.org/10.4081/microscopie.2020.9188
Accepted: 21 June 2020
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A case of Parry Romberg syndrome (PRS) in a 7-year-old girl is described. Ultrastructural investigations, supported by clinical evaluations, were performed on both affected and unaffected skin. Connective tissue abnormalities were mainly observed in the diseased area, where an increased number of mast cells can be observed, and collagen is organized in large bundles with fibrils of heterogeneous diameters. Data are suggestive for increased matrix remodeling in the affected skin.
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