From PCL/HA powder to bioresorbable scaffold via laser powder bed fusion


Published: 4 June 2020
Abstract Views: 401
PDF: 204
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • Maria Laura Gatto Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.
  • Gianni Barucca Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.
  • Paolo Mengucci Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.

Bone bioresorbable scaffold substitutes bone physiological functionalities during its life span. In addition to biological and mechanical performances, bioresorbable scaffolds have to show structure material homogeneity, non-toxic degradation products and degradation rate proportional to new bone growth. In this study, the compositional and structural characteristics of bioresorbable polycaprolactone (PCL)/ hydroxyapatite (HA) scaffolds, produced via laser powder bed fusion in lattice forms (with diamond and rhombic dodecahedron elementary unit cells, respectively), were analyzed in terms of comparison between starting powder and manufactured scaffolds. Scaffolds showed the achievement of: i) isotropic structure, necessary to obtain good mechanical properties; ii) chemical composition enhancing cells adhesion to the scaffold surface and iii) crystallinity that preserves structure integrity in physiological environment.


Gatto, M. L., Barucca, G., & Mengucci, P. (2020). From PCL/HA powder to bioresorbable scaffold via laser powder bed fusion. Microscopie, 31(1). https://doi.org/10.4081/microscopie.2020.9101

Downloads

Download data is not yet available.

Citations