From PCL/HA powder to bioresorbable scaffold via laser powder bed fusion


Published: 4 June 2020
Abstract Views: 402
PDF: 207
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Authors

  • Maria Laura Gatto Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.
  • Gianni Barucca Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.
  • Paolo Mengucci Department of Materials, Environmental Sciences and Urban Planning, Università Politecnica delle Marche, Ancona, Italy.

Bone bioresorbable scaffold substitutes bone physiological functionalities during its life span. In addition to biological and mechanical performances, bioresorbable scaffolds have to show structure material homogeneity, non-toxic degradation products and degradation rate proportional to new bone growth. In this study, the compositional and structural characteristics of bioresorbable polycaprolactone (PCL)/ hydroxyapatite (HA) scaffolds, produced via laser powder bed fusion in lattice forms (with diamond and rhombic dodecahedron elementary unit cells, respectively), were analyzed in terms of comparison between starting powder and manufactured scaffolds. Scaffolds showed the achievement of: i) isotropic structure, necessary to obtain good mechanical properties; ii) chemical composition enhancing cells adhesion to the scaffold surface and iii) crystallinity that preserves structure integrity in physiological environment.


Gatto, M. L., Barucca, G., & Mengucci, P. (2020). From PCL/HA powder to bioresorbable scaffold via laser powder bed fusion. Microscopie, 31(1). https://doi.org/10.4081/microscopie.2020.9101

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