https://doi.org/10.4081/jbr.2021.9287
Effect of exercise training on gene expression of adiponectin and its receptors in testicles and sex hormones in diabetic rats
Submitted: July 29, 2020
Accepted: December 13, 2020
Published: February 18, 2021
Accepted: December 13, 2020
Abstract Views: 2231
PDF: 560
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Adiponectin and its receptors are expressed in the male reproductive system, which play a role in regulating male sex hormones and fertility. Diabetes was induced by Streptozotocin-Nicotinamide (STZ-NA i.p) in rats and after performing the trainings, adiponectin gene expression and its receptors in the testis were evaluated using real time PCR, and blood serum was then used in order to assess FSH, LH and testosterone. The STZ-NA significantly increased the fasting blood glucose, gene expression of adiponectin AdipoR1 in the testicles of diabetic rats. A significant reduction in serum testosterone and LH levels were observed in the diabetic group. Resistance and endurance training decreased blood glucose, adiponectin and AdipoR1 gene, and also increased the serum testosterone and LH levels in diabetic rats. Overall, our data suggest the role played by training in improve expression of adiponectin and AdipoR1 gene by increasing the serum testosterone and LH levels in type 2 diabetic rats.
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How to Cite
Nadi, Z., Bayat, M., Karami, H., Parastesh, M., & Bayat, P. D. (2021). Effect of exercise training on gene expression of adiponectin and its receptors in testicles and sex hormones in diabetic rats. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 94(1). https://doi.org/10.4081/jbr.2021.9287
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