https://doi.org/10.4081/jbr.2023.11346
Wound healing and analgesic effects of Brocchia cinerea essential oil in experimental animals
Submitted: March 31, 2023
Accepted: July 18, 2023
Published: September 5, 2023
Accepted: July 18, 2023
Abstract Views: 1093
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
This study aimed to identify the main components of the essential oil extracted from Brocchia cinerea (Delile) Vis. via hydrodistillation and investigate its in vivo wound healing and analgesic properties. Thujone, santolina triene, camphor, and 1,8-cineole were among the compounds detected. Wounds were induced in mice and treated with essential oil, which resulted in accelerated wound healing and repair through topical application (88.1±1.1%). The study also evaluated the analgesic activity of the essential oil by administering intraperitoneal injections of acetic acid to mice. The results showed that B. cinerea essential oil at a dose of 400 mg/kg strongly inhibited pain, with a pain inhibition percentage of 95.5%. These findings indicate that the essential oil of B. cinerea has potential as a source of bioactive compounds that may have synergistic effects. Based on these results, the use of B. cinerea for therapeutic purposes in preventing pain and promoting wound healing is supported. These findings highlight the potential of B. cinerea in paving the way for future research aimed at the development of clinically valuable products.
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How to Cite
Lakache, Z., Aliboudhar, H., Sadallah, M., Hacib, H., Fekiri, M., Zergat, A. I., Tounsi, H., & Kameli, A. (2023). Wound healing and analgesic effects of <i>Brocchia cinerea</i> essential oil in experimental animals. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 96(2). https://doi.org/10.4081/jbr.2023.11346
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