https://doi.org/10.4081/jbr.1999.10856
THE CORONARY VASCULATURE AND THE MYOCARDIUM
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
It has been reported that the activity of bradykinin on vascular endothelial receptors results in vasodilatation ( 1-3) due to the release of both nitric oxide (NO) and the so called endothelial-derived hyperpolarizing factor (EDHF) (4-7). It has also been suggested that in the rat bradykinin-induced vasodilatation is not mediated by NO but by EDHF only (2). Although a number of compounds can cause hyperpolarization of the smooth muscle fibres .of the vascular wall, in the coronary bed of the rat and some other species EDHF has been identified with a non-prostanoid autacoid produced by the activity of cytochrome P-450 on arachidonic acid (3). This autacoid is likely to be one of the epoxiecocystrienoic acids (EETs) (8,9). [...]
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.