Endothelial Paracrine Action

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Some endothelial-derived compounds are able to cross the membrane and regulate the function of other nearby cells. The coronary arteries release endothelial factors and as such mediate paracrine action both on myocardiocytes and smooth muscle cells.Among the endothelial vasoactive substances released from the coronary arteries are Endothelial Derived Relaxing Factor (EDRF), Endothelial Derived Hyperpolarizing Factors (EDHFs), prostaglandins and endothelines 1,2,3 (ET-1, ET-2, ET-3). [...]

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Mancardi, D. . (2003). Endothelial Paracrine Action. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 79(1). https://doi.org/10.4081/jbr.2003.10508