Spectral characteristics of the internal jugular vein and central venous pressure pulses: a proof of concept study

  • Clive Beggs Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, United Kingdom.
  • Valentina Tavoni Hub Centre for Venous and Lymphatics Diseases of Emilia Romagna Region, University Hospital of Ferrara, Ferrara, Italy.
  • Erica Menegatti Hub Centre for Venous and Lymphatics Diseases of Emilia Romagna Region, University Hospital of Ferrara, Ferrara, Italy; Department of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy.
  • Mirko Tessari Hub Centre for Venous and Lymphatics Diseases of Emilia Romagna Region, University Hospital of Ferrara, Ferrara, Italy.
  • Luca Giovanardi Service of Clinical Engineering, University Hospital of Ferrara, Ferrara, Italy.
  • Riccardo Ragazzi Department of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy.
  • Anna Maria Malagoni | mlgnmr@unife.it Hub Centre for Venous and Lymphatics Diseases of Emilia Romagna Region, University Hospital of Ferrara, Ferrara, Italy.

Abstract

In this proof-of-concept study the impact of central venous pressure (CVP) on internal jugular veins cross-sectional area (CSA) and blood flow time-average velocity (TAV) was evaluated in eight subjects, with the aim of understanding the drivers of the jugular venous pulse. CVP was measured using a central venous catheter while CSA variation and TAV along a cardiac cycle were acquired using ultrasound. Analysis of CVP, CSA and TAV time-series signals revealed TAV and CSA to lag behind CVP by on average 0.129 s and 0.138 s, with an inverse correlation between CSA and TAV (r= –0.316). The respective autocorrelation signals were strongly correlated (mean r=0.729-0.764), with mean CSA periodicity being 1.062 Hz. Fourier analysis revealed the frequency spectrums of CVP, TAV and CSA signals to be dominated by frequencies at approximately 1 and 2 Hz, with those >1 Hz greatly attenuated in the CSA signal. Because the autocorrelograms and periodograms of the respective signals were aligned and dominated by the same underlying frequencies, this suggested that they are more easily interpreted in the frequency domain rather than the time domain.

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Published
2021-03-29
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Original Articles
Keywords:
Jugular venous pulse, central venous pressure, spectral signals, ultrasound.
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How to Cite
Beggs, C., Tavoni, V., Menegatti, E., Tessari, M., Giovanardi, L., Ragazzi, R., & Malagoni, A. M. (2021). Spectral characteristics of the internal jugular vein and central venous pressure pulses: a proof of concept study. Veins and Lymphatics, 10(1). https://doi.org/10.4081/vl.2021.9732