Review Articles
Vol. 2 No. 1 (2018)
https://doi.org/10.4081/tmr.7002

Relationship between type 2 diabetes and pancreatic cancer

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Received: 17 August 2017
Published: 19 November 2018
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Pancreas, Cancer, Diabetes

Authors

M. Temel Yilmaz
Diabetes Application and Research Center (DIYAM), Istanbul University, Sehremini; Department of Internal Medicine, Endocrinology and Metabolic Diseases Division, Istanbul Medicine Faculty, Istanbul University, Capa; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Sehremini, Istanbul, Türkiye.
Ali Osman Gürol
ogurol@yahoo.com
Diabetes Application and Research Center (DIYAM), Istanbul University, Sehremini; Department of Immunology, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Sehremini, Istanbul, Türkiye.
Diabetes mellitus and cancer are conditions that constitute a serious problem for the health of the world’s population, and their co-existence in the same person is becoming increasingly common. Glucose metabolism and the presence of insulin in inflammatory situations appear to be the main factors driving this association, where hyperinsulinemia has been shown to contribute to an increase in risk of association between type 2 diabetes and cancer. Therefore, administering lower levels of exogenously administered insulin to patients with type 1 diabetes would decrease their risk of developing cancer when compared to patients with type 2 diabetes. The results from animal experiments seem promising in terms of pharmacological treatment.

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Relationship between type 2 diabetes and pancreatic cancer. (2018). Translational Medicine Reports, 2(1). https://doi.org/10.4081/tmr.7002
Copyright (c) 2018 M. Temel Yilmaz, Ali Osman Gürol Creative Commons License

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