Oxygen-ozone therapy and local administration induced pain


https://doi.org/10.4081/ozone.2017.6742

Authors

  • Marco Mainini
    mamainini@yahoo.it
    Department of Anesthesiology, Intensive Care, Pain Medicine and Ozone Therapy, Second University of Naples, Naples, Italy.
  • Maria Laura Rosato Department of Anesthesiology, Intensive Care, Pain Medicine and Ozone Therapy, Second University of Naples, Naples, Italy.
  • Margherita Luongo Center of Oxygen-Ozone Therapy, Master of Oxygen-Ozone Therapy, Second University of Naples, Naples, Italy.
  • Luigi Mascolo Center of Oxygen-Ozone Therapy, Master of Oxygen-Ozone Therapy, Second University of Naples, Naples, Italy.
  • Silvana Mattera Department of Anesthesiology, Intensive Care, Pain Medicine and Ozone Therapy, Second University of Naples, Naples, Italy.
  • Luca Schiaffino Center of Oxygen-Ozone Therapy, Master of Oxygen-Ozone Therapy, Second University of Naples, Naples, Italy.
Oxygen-ozone (O²-O³) therapy is emerging in the treatment of many diseases. This kind of treatment is characterized by a few side effects. When oxygen-ozone mixture is administered through subcutaneous or intramuscular infiltration, often patients refer pain or burning sensation in the site of injection. The aim of our study is to evaluate intensity and duration of this side effect during treatments.