TY - JOUR AU - Maioli, Elisabetta AU - Bandettini, Roberto AU - Battolla, Enrico AU - Bona, Rosalba AU - Bottaro, Luigi Carlo AU - Brunetti, Rinaldo AU - Capuzzo, Roberto AU - Devoto, Gian Luigi AU - Dono, Maria AU - Dusi, Andrea AU - Fedele, Manuela AU - Ferro, Giorgia AU - Giusto, Giovanni Rosario AU - Mannelli, Stefania AU - Massucco, Federica AU - Mazzarello, Maria Gabriella AU - Mori, Marco AU - Perfumo, Mascja AU - Piatti, Gabriella AU - Reali, Silvia AU - Ronca, Agostina AU - Santoriello, Luisa AU - Serra, Domizio AU - Usiglio, David AU - Marchese, Anna AU - Debbia, Eugenio A. PY - 2006/12/31 Y2 - 2024/03/28 TI - Indagine sulla diffusione di stafilococchi resistenti alla meticillina in Liguria JF - Microbiologia Medica JA - Microbiol Med VL - 21 IS - 4 SE - Original Articles DO - 10.4081/mm.2006.2912 UR - https://www.pagepressjournals.org/mm/article/view/2912 SP - AB - Introduction. Staphylococcus aureus is a major opportunistic pathogen especially in nosocomial settings. An increasing proportion of strains has intrinsic resistance to methicillin (MRSA) and recent reports documented the emergence of MRSA also in the community.The aim of this study was to evaluate methicillin-resistance in Liguria. Methods. 767 isolates of Staphylococcus spp have been collected from 10 laboratories, including 508 S. aureus: 292 (57.5%) hospital-acquired, 188 (37%) community-acquired, and 28 (5.5%) from healthcare settings; 259 coagulase- negative staphylococci (CNS): (193 (74.5%) hospital-acquired, 56 (21.6%) community-acquired, and 10 (3.9%) healthcare settings. Susceptibility tests were carried out by the disk diffusion method (CLSI, 2006) using cefoxitin (CFX) (Oxoid, Milan). MRSA has been also evaluated by PBP2’ latex agglutination test (Oxoid, Milan) on 52 randomly selected S. aureus. Results. The data obtained indicated an incidence of MRSA in nosocomial settings up to 45.2%, while among the community-acquired isolates the percentage was 6.4%. With respect to CNS the figures were 61,8% and 10,6% for the nosocomial-and community-acquired organisms respectively. A 99% agreement between data of the coordinating centre and the various laboratories was found. Methicillin-resistance was confirmed in 52 S. aureus by PBP2’ latex agglutination test. Conclusions. Present findings indicate that MRSA in community in the Ligurian area exists and this phenomenon requires future surveillance. ER -