Diagnosing HIV “window phase” in routine laboratory: a teaching case

  • Roberta Valentina Marotta | roberta.marotta@ao-sanpaolo.it
  • Rossana Baccalini
  • Alessandro Mauri
  • Marco Facca
  • Gabriella Palanza
  • Manuela Martucci
  • Raffaella Seminati
  • Gianlodovico Melzi d’Eril

Abstract

Human immunodeficiency virus (HIV) is the causative agent of acquired immunodeficiency syndrome (AIDS). It is a retrovirus that inserts itself into the host’s DNA and use the host – cell’s replication mechanisms for its own perpetuation. Two distinct species of HIV (HIV 1 and HIV 2) have been identified and they have a different global distribution. In this paper we describe a case of HIV early infection in an italian man of fourty years old. From this example we want to stress the importance to consider with high attention the validation of a negative index of HIV antibodies.We advise to follow this procedure that allows to avoid the risk to report a false negative.

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Published
2011-12-31
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Section
Clinical Cases
Keywords:
HIV, laboratory diagnosis, early infection
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How to Cite
Marotta, R., Baccalini, R., Mauri, A., Facca, M., Palanza, G., Martucci, M., Seminati, R., & d’Eril, G. (2011). Diagnosing HIV “window phase” in routine laboratory: a teaching case. Microbiologia Medica, 26(4). https://doi.org/10.4081/mm.2011.2346

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