Genital Chlamydia trachomatis infections

  • Maria Agnese Latino | maglat@hotmail.com
  • Daniela De Maria
  • Andrea Caneparo
  • Claudia Rosso
  • Gianfranco De Intinis
  • Anna Maria Calì
  • Pierangelo Clerici
  • Marco Cusini
  • Ivano Dal Conte
  • Tiziano Maggino
  • Enrico Magliano
  • Alfonso Panuccio
  • Roberto Pozzoli
  • Mario Rassu
  • Barbara Suligoi
  • Riccardo Terramocci

Abstract

Chlamydia trachomatis (C.t.) infection is one of the most prevalent sexually transmitted disease in Europe and in developed countries. The main biological features and pathogenic mechanisms of C.t. infection are summarized in this review. It usually occurs without symptoms and often goes undiagnosed. If untreated, it can cause severe consequences for women, including pelvic inflammatory disease (PID), ectopic pregnancy and tubal infertility. Several studies have found that Chlamydia is more common among young women <25 years old, with multiple sexual partners within six months and non protected intercourses. Because re-infection rates are high, complications may be reduced if partners are treated and women re-tested. This paper emphasizes the importance of counselling and prevention programs and underlines that selective screening of high-risk population remains an essential component of C.t. control. In the last years, the detection of C.t. infection has been improved in sensitivity and specificity.We describe the main diagnostic techniques, from culture, enzyme immunoassay (EIA), direct fluorescent-antibody assay (DFA) to the new DNA-based test systems. Actually, NAATs (nucleic acid amplification tests) are regarded as the gold standard diagnostic techniques for chlamydial infections.

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Published
2008-03-31
Info
Issue
Section
Reviews
Keywords:
Chlamydia trachomatis, epidemiology, risk factors, diagnosis
Statistics
  • Abstract views: 1401

  • PDF: 1211
How to Cite
Latino, M. A., De Maria, D., Caneparo, A., Rosso, C., De Intinis, G., Calì, A. M., Clerici, P., Cusini, M., Dal Conte, I., Maggino, T., Magliano, E., Panuccio, A., Pozzoli, R., Rassu, M., Suligoi, B., & Terramocci, R. (2008). Genital Chlamydia trachomatis infections. Microbiologia Medica, 23(1). https://doi.org/10.4081/mm.2008.2591

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