Isolation of multidrug-resistant Enterobacter cloacae and comparison among clavulanate-tazobactam and sulbactam-synergy by using a double-disk synergy test

  • Vincenzo Savini | vincsavi@yahoo.it
  • Fabio Febbo
  • Andrea Balbinot
  • Marzia Talia
  • Chiara Catavitello
  • Assunta Manna
  • Fabio Di Berardino
  • Francesca Fioritoni
  • Daniela Carlino
  • Giovanni Di Bonaventura
  • Domenico D’Antonio

Abstract

False negative results of double-disk synergy test with Enterobacter cloacae are common, as AmpC-enzymes may mask ESBLs elaboration. We increased the sensitivity of the method by using both clavulanate- and tazobactam/sulbactam; hence, we suggest to use all the three inhibitors to screen ESBLs in AmpC ß-lactamases producing organisms.

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Published
2008-06-30
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Section
Short Communications
Keywords:
Enterobacter cloacae, ESBLs, double-disk synergy test
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How to Cite
Savini, V., Febbo, F., Balbinot, A., Talia, M., Catavitello, C., Manna, A., Di Berardino, F., Fioritoni, F., Carlino, D., Di Bonaventura, G., & D’Antonio, D. (2008). Isolation of multidrug-resistant Enterobacter cloacae and comparison among clavulanate-tazobactam and sulbactam-synergy by using a double-disk synergy test. Microbiologia Medica, 23(2). https://doi.org/10.4081/mm.2008.2587

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