Phages and phage therapy: past, present and future

  • Nour Essa Cystic Fibrosis Diagnostic Unit, Laboratory and Pediatric Departements, Children’s Hospital and Research Institute Bambino Gesù, Rome, Italy.
  • Martina Rossitto Cystic Fibrosis Diagnostic Unit, Laboratory and Pediatric Departements, Children’s Hospital and Research Institute Bambino Gesù, Rome, Italy.
  • Ersilia Vita Fiscarelli | evita.fiscarelli@opbg.net Cystic Fibrosis Diagnostic Unit, Laboratory and Pediatric Departements, Children’s Hospital and Research Institute Bambino Gesù, Rome, Italy.

Abstract

Bacteriophages are viruses that infect bacteria. Since their discovery in the last century, they have proved their effectiveness in biocontrol of bacteria. In this mini-review, we provide a brief history of bacteriophages, their life cycle and classification. We also discuss the potential use of bacteriophage in clinical therapy as an alternative to antibiotics, comparing their advantages and disadvantages.

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Published
2020-06-11
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Issue
Section
Reviews
Keywords:
Bacteriophages, phage therapy, antibiotics
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How to Cite
Essa, N., Rossitto, M., & Fiscarelli, E. (2020). Phages and phage therapy: past, present and future. Microbiologia Medica, 35(1). https://doi.org/10.4081/mm.2020.8709