JUVENILE DIFFUSE LARYNGEAL PAPILLOMATOSIS: CASE REPORT


Submitted: 10 January 2012
Accepted: 10 January 2012
Published: 10 January 2012
Abstract Views: 1017
PDF: 1040
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • A. Burgio Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • G. Vessio Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • C. Varetti Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • F. Fanti Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • Al. Bulotta Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • D. Meucci Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • M. Pavone Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
  • M. Messina Division of Pediatric Surgery, Department of Pediatrics, Obstetrics and Reproductive Medicine, University Of Siena, Italy.
Introduction. Juvenile laryngeal papillomatosis is a rare benign neoplasm of the larynx in children; incidence is estimated about 4.3/100.000 children and extralaryngeal spread to the lower airway is relatively uncommon. Although it has a clear viral origin factors that characterize the onset and progress are still uncertain. Materials and methods. We report a 7 year old boy with chronic dysphonia, dyspnoea, haemoptysis and anemia who was admitted in our Clinic. The patient was submitted to left cord vocal biopsy for hoarseness. At 2 years it was diagnosed squamous papilloma and it was managed with microdebrider in another country . A laryngo-tracheo-bronchoscopy was performed with biopsies for viral identification and histology, treatment with laser CO2, tracheotomy for diffuse papillomatosis and intralaryngeal antiviral injection. The papillomatosis was extended in glottic and subglottic. Histological report is laryngeal papillomatosis due to HPV types 11. Identification of HPV genotypes was based on PCR. Results. He had 3 procedures of laser CO2 and the mean time between two consecutive surgeries was 20 days. A third laryngoscopy, after 5 week, found no lesion, no scar formation, no bleeding. The patient was discharged after 3 mounth. Conclusion. The natural history of laryngeal papillomatosis is highly variable and unpredictable. The disease may undergo spontaneous remission, persist in a stable state requiring only periodic surgical treatment, or may be aggressive, requiring surgical treatment every few days to weeks and consideration of adjuvant medical therapy.

Burgio, A., Vessio, G., Varetti, C., Fanti, F., Bulotta, A., Meucci, D., Pavone, M., & Messina, M. (2012). JUVENILE DIFFUSE LARYNGEAL PAPILLOMATOSIS: CASE REPORT. Journal of the Siena Academy of Sciences, 1(1), 97–99. https://doi.org/10.4081/jsas.2009.351

Downloads

Download data is not yet available.

Citations