Anti-tissue transglutaminase antibodies and EEG pattern in celiac patients on prolonged gluten-free diet

A. Berio; G. Badolati; G. Mangiante; E. Calcagno; A. Piazzi

doi:10.4081/jbr.2013.3666

Anti-tissue transglutaminase antibodies and EEG pattern in celiac patients on prolonged gluten-free diet

https://doi.org/10.4081/jbr.2013.3666

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Vol. 86 No. 1 (2013)

Submitted: April 10, 2014
Accepted: April 10, 2014

Published: January 30, 2013

Transglutaminase, celiac disease, EEG, diet

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The Authors investigate the relationship between serum anti-tTG antibodies and EEG pattern in 12 celiac patients of various age on gluten-free diet for 1-10 years. In a group of 6 patients with good compliance with the diet, anti-tTG antibodies were normal in all and EEG in 5; in another group of 6 patients with poor compliance with the diet, serum anti-tTG antibodies were raised in all; EEG abnormalities of various gravity were reported in 5 patients. The concomitance of raised anti-tTG antibodies and EEG abnormalities is stressed, as possible expression of an immune-inflammatory reaction persistent in Central Nervous System.

Berio, A., Badolati, G., Mangiante, G., Calcagno, E., & Piazzi, A. (2013). Anti-tissue transglutaminase antibodies and EEG pattern in celiac patients on prolonged gluten-free diet. Journal of Biological Research - Bollettino Della Società Italiana Di Biologia Sperimentale, 86(1). https://doi.org/10.4081/jbr.2013.3666