C-reactive protein as a marker of infection in children with severe acute malnutrition in Khartoum state, Sudan


Submitted: 21 November 2016
Accepted: 2 February 2017
Published: 9 August 2017
Abstract Views: 3477
PDF: 630
HTML: 4193
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Severe acute malnutrition and acute systemic infection are often synergistic in children and lead to considerable mortality. The main aim of this research was to determine whether children with severe acute malnutrition can mount an acute phase reactant response measured by C-reactive protein. This was a descriptive, cross-sectional, hospital-based study that was carried out in the five main children hospitals in Khartoum state, from November 1st, 2012 to March 1st, 2013. 132 children with severe acute malnutrition were included in the study. Data collection included history, examination and C-reactive protein measurement. The data were analyzed using Statistical Package for Social Sciences (SPSS) for descriptive and inferential statistics. The main results revealed that 93(70.5%) children between 12-23 months of age and most of them had marasmus. Diarrhoea was the commonest presenting symptoms in 86.4%, followed by fever and vomiting. Most of the children (82.6%) had positive C-reactive protein with variable levels. In conclusion malnourished children are able to synthesize C-reactive protein in response to an infectious process and the magnitude of this response is increased in those with severe infections.

Abdelmoneim E.M. Kheir, Department of Paediatrics and Child Health, University of Khartoum and Soba University Hospital, Khartoum

Associate professor

Department of Paediatrics

faculty of medicine

university of Khartoum

Balla G. Gebreel, Department of Paediatrics and Child Health, University of Khartoum and Soba University Hospital, Khartoum
Department of Paediatrics
Soba University Hospital
       Khartoum

Supporting Agencies

None

Kheir, A. E., & Gebreel, B. G. (2017). C-reactive protein as a marker of infection in children with severe acute malnutrition in Khartoum state, Sudan. Healthcare in Low-Resource Settings, 5(1). https://doi.org/10.4081/hls.2017.6401

Downloads

Download data is not yet available.

Citations