https://doi.org/10.4081/hls.2023.11323
Value of biochemical markers in predicting outcome of COVID-19 infection in University Hospital, Alexandria, Egypt
Submitted: 18 March 2023
Accepted: 2 May 2023
Published: 8 June 2023
Accepted: 2 May 2023
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
This paper aims to examine the value of different biochemical markers in predicting the outcome of COVID-19 infection. A total of 140 patients with confirmed COVID-19 infection by polymerase chain reaction (PCR), different biochemical markers were tested, their relation to the outcome of the disease was monitored, and the most reliable tests were determined. The study found a significant correlation between all evaluated biochemical markers and severity of the disease, including C-reactive protein (CRP), D-dimer, alanine aminotransferase (ALT), Aspartate aminotransferase (AST), prothrombin time (PT), activated partial thromboplastin time (aPTT). In addition, ferritin, lactate dehydrogenase (LDH), procalcitonin (PCT) and Pro- Brain natriuretic peptide (proBNP) demonstrated highly sensitivity and specificity as well as significant prognostic performance. These markers were also independently significant in predicting mortality. Early assessment of biochemical markers in patients with COVID-19 can help clinicians in tailoring treatment and providing more intensive care to those with greater mortality risk. In particular, the assessment of ferritin, LDH, procalcitonin and proBNP can independently predict mortality.
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How to Cite
Rashad Mostafa, N., Ali, A. A. M., Ezzat, R. M., Bakry, M. K., & Marzo, R. R. (2023). Value of biochemical markers in predicting outcome of COVID-19 infection in University Hospital, Alexandria, Egypt. Healthcare in Low-Resource Settings, 11(s2). https://doi.org/10.4081/hls.2023.11323
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