Effects of home-based exercise program on physical functioning of hemodialysis patients: A randomized controlled trial

Submitted: 6 April 2022
Accepted: 5 June 2022
Published: 13 June 2022
Abstract Views: 1489
PDF: 323
HTML: 57
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

Chronic kidney disease is one of the leading causes of death, which is often neglected due to lack of knowledge and resources. The objective of this study was to determine the effects of home-based exercise on physical functioning, quality of life and fatigue assessment for patients on hemodialysis. A randomized control trial was conducted, with participants divided into two groups. Twenty-six (26) participants were enrolled, and were assigned equally to each group. The control group received hospital-based care, and the intervention group received a home exercise program. Both groups received three sessions per week, for six weeks. Outcome measures included six-minute walk test, standing balance, 4-metre gait speed, chair stand, fatigue assessment scale and quality of life. Significant improvement in sixminute walk test, fatigue assessment scale, 4 meter gait speed, chair stand test and standing balance was noted in the intervention group as compared with control group. This study concluded that aerobic and resistance exercises are more effective in improving the functional outcomes of patients on hemodialysis as compared to routine physical therapy.

Dimensions

Altmetric

PlumX Metrics

Downloads

Download data is not yet available.

Citations

National Kidney Foundation. K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis 2002;39:S1.
Gansevoort RT, Correa-Rotter R, Hemmelgarn BR, et al. Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention. Lancet 2013;382:339-52.
Bikbov B, Purcell CA, Levey AS, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 2020;395:709-33.
Rehman IU, Munib S, Ramadas A, Khan TM. Prevalence of chronic kidney disease-associated pruritus, and association with sleep quality among hemodialysis patients in Pakistan. PloS One 2018;13:e0207758.
Ralston SH, Penman ID, Strachan MWJ, Hobson R. Davidson’s principles and practice of medicine. Elsevier Health Sciences, 23rd ed.; 2018.
Ren J, Dai C. Pathophysiology of Chronic Kidney Disease. In: Yang J, He W (eds). Chronic Kidney Disease. Springer, Singapore; 2020.
Colledge NR, Walker BR, Ralston S, Davidson S. Davidson’s principles and practice of medicine. Edinburgh, Churchill Livingstone/Elsevier; 2010.
Pinelli NR, Moore CL, Tomasello S. Incretin-based therapy in chronic kidney disease. Adv Chronic Kidney Dis 2010;17:439-49.
Davison SN, Tupala B, Wasylynuk BA, et al. Recommendations for the care of patients receiving conservative kidney management: Focus on management of CKD and symptoms. Clin J Am Soc Nephrol 2019;14:626-34.
Koncicki HM, Brennan F, Vinen K, Davison SN. An approach to pain management in end stage renal disease: Considerations for general management and intradialytic symptoms. Sem Dialysis 2015;28:384-91.
Chen TK, Knicely DH, Grams ME. Chronic kidney disease diagnosis and management: a review. JAMA 2019;322:1294-304.
Joshi S, Hashmi S, Shah S, Kalantar-Zadeh K. Plant-based diets for prevention and management of chronic kidney disease. Curr Opin Nephrol Hyperten 2020;29:16-21.
Hall YN, Larive B, Painter P, et al. Effects of six versus three times per week hemodialysis on physical performance, health, and functioning: Frequent Hemodialysis Network (FHN) randomized trials. Clin J Am Soc Nephrol 2012;7:782–94.
Neto JR, e Castro LM, de Oliveira FS, et al. Comparison between two physiotherapy protocols for patients with chronic kidney disease on dialysis. J Phys Ther Sci 2016;28:1644-50.
Zhang F, Bai Y, Zhao X, et al. The impact of exercise intervention for patients undergoing hemodialysis on fatigue and quality of life: A protocol for systematic review and meta-analysis. Medicine (Baltimore) 2020;99:e21394.
Gravina EP, Pinheiro BV, da Silva Jesus LA, et al. Effects of long-term aerobic training and detraining on functional capacity and quality of life in hemodialysis patients: A pilot study. Int J Artific Organs 2020;43:411-5.
Cid-Ruzafa J, Damian-Moreno J. Assessment of physical disability: Barthel index Rev. ESP. Health public 1997;71:127-37.
Bessa B, Moraes C, Barros A, et al. Effects of intradialytic resistance trainning on functional capacity, strengh and body composition in hemodialysis patients. Kidney Res Clin Pract 2012;31:A59.
Anees M, Ibrahim M, Imtiaz M, et al. Translation, validation and reliability of the kidney diseases quality of life-short form (KDQOL-SF Form) tool in Urdu. J Coll Physicians Surg Pak 2016;26:651-4.
Soares V. Influence of inspiratory muscle training on respiratory function and quality of life in patients with chronic kidney disease on hemodialysis and the relationship with body composition and aerobic capacity. 2014. Available at: https://repositorio.bc.ufg.br/tede/handle/tede/3987
Matsuzawa R, Matsunaga A, Wang G, et al. Habitual physical activity measured by accelerometer and survival in maintenance hemodialysis patients. Clin J Am Soc Nephrol 2012;7:2010–16.
Donoghue OA, Savva GM, Cronin H, et al. Using timed up and go and usual gait speed to predict incident disability in daily activities among community-dwelling adults aged 65 and older. Arch Phys Med Rehabil 2014;95:1954–61.
Caner C, Ozlem S, Yavuz Y, et al. The effects of exercise during hemodialysis on adequacy. Hemodialysis Int 2005;9:77.
Roxo R, Bertoni Xavier V, Miorin LA, et al. Impact of neuromuscular electrical stimulation on functional capacity of patients with chronic kidney disease on hemodialysis. J Bras Nefrol 2016;38:344‐50.
Koufaki P, Mercer TH, Naish PF. Effects of exercise training on aerobic and functional capacity of end-stage renal disease patients. Clin Physiol Funct Imaging 2002;22:115–24.
De Buyser SL, Petrovic M, Taes YE, et al. Physical function measurements predict mortality in ambulatory older men. Eur J Clin Invest 2013;43:379–86.
Twisk J, de Vente W. Attrition in longitudinal studies. How to deal with missing data. J Clin Epidemiol 2002;55:329–37.
Martins MR, Cestarino CB. Qualidade de vida de pessoas com doença renal crônica em tratamento hemodialítico. [Quality of life of people with chronic kidney disease on hemodialysis treatment.] [Article in Portuguese] eRev Latinoam Enferm 2005;13:670–6.
Uchiyama K, Washida N, Muraoka K, et al. Exercise capacity and association with quality of life in peritoneal dialysis patients. Peritoneal Dialysis Int 2019;39:66-73.
Flisinski M, Brymora A, Elminowska-Wenda G, et al. Morphometric analysis of muscle fibre types in rat locomotor and postural skeletal muscles in different stages of chronic kidney disease. J Physiol Pharmacol 2014;65:567–576.
Stolić RV, Mihailović B, Matijašević IR, Jakšić MD. Effects of physiotherapy in patients treated with chronic hemodialysis. Biomedicinska istraživanja 2018;9:103-11.
Moorthi RN, Avin KG. Clinical relevance of sarcopenia in chronic kidney disease. Curr Opin Nephrol Hyperten 2017;26:219.

How to Cite

Kumar, N., Sheraz, S., Pereira, F. A., Razzaq, A., Angela, C., & Saad, S. M. (2022). Effects of home-based exercise program on physical functioning of hemodialysis patients: A randomized controlled trial. Healthcare in Low-Resource Settings, 10(1). https://doi.org/10.4081/hls.2022.10499