QTc prolongation during the SARS-CoV-2 outbreak: clinical risk management through hospital training course, focus on elderly patients

  • Nicola Forni SC Malattie Infettive, ASL-1 Imperiese Sanremo, Italy.
  • Valentina Boasi SC Cardiologia, ASL-1 Imperiese Sanremo, Italy.
  • Katiuscia Sciole SC Malattie Infettive, ASL-1 Imperiese Sanremo, Italy.
  • Silvia Borile SC Cardiologia, ASL-1 Imperiese Sanremo, Italy.
  • Nicoletta Pingelli SC Cardiologia, ASL-1 Imperiese Sanremo, Italy.
  • Domenico Marra SC Laboratorio Analisi, ASL-1 Imperiese, Italy.
  • Sara Tita Farinella SC Malattie Infettive, ASL-1 Imperiese Sanremo, Italy.
  • Giovanni Cenderello | g.cenderello@asl1.liguria.it SC Malattie Infettive, ASL-1 Imperiese Sanremo, Italy.
  • Federico Ariel Sanchez SC Cardiologia, ASL-1 Imperiese Sanremo, Italy.

Abstract

The recent outbreak exposed doctors to a new challenge: treating people without any scientific evidence. All molecules combined in treatment schedules were merged on the basis of weak and anecdotal data so, the recommendations are constantly changing. In this context it is either mandatory for clinicians focusing on the different treatment options and on probable side effects of each molecules. It is well acquired that among elderly within same age group and strain, the outcome will differ according to each patient’s frailty. Moreover, old and frail people are particularly exposed to a double risk: the first one is the age-related mortality and the second one the susceptibility (also age related too) to side effects. Aim of our paper is reporting our experience in reducing toxicity with a constant action of scientific update and subsequent modification in clinical management protocols. Main focus was on frail patients and cardiologic risk-related to hydroxychloroquine.

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Published
2020-08-27
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Original Articles
Keywords:
Hydroxychloroquine, QTc prolongation, COVID-19, frail patients.
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How to Cite
Forni, N., Boasi, V., Sciole, K., Borile, S., Pingelli, N., Marra, D., Tita Farinella, S., Cenderello, G., & Sanchez, F. A. (2020). QTc prolongation during the SARS-CoV-2 outbreak: clinical risk management through hospital training course, focus on elderly patients. Geriatric Care, 6(3). https://doi.org/10.4081/gc.2020.9128