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It is essential for welfare systems to predict the health and care needs of people with chronic diseases. The Multidimensional Prognostic Index (MPI) proved excellent accuracy in predicting negative health outcomes. Recently, a selfadministered version of MPI (SELFY-MPI) was developed and validated in community- dwelling subjects showing an excellent agreement between the two instruments regardless of age. This is a feasibility study concerns the implementation of SELFYMPI in five European countries. The SELFY-MPI includes the self-administration of Barthel Index, Instrumental Activities of daily Living (IADL), Test Your Memory (TYM) Test, Mini Nutritional Assessment-Short Form (MNA-SF), comorbidity, number of medications, and the Gijon’s Socio-Familial Evaluation Scale (SFES). A descriptive analysis was performed on the data collected. 300 subjects (mean age 62 years, range 19-88 years; male/female ratio 0.81) completed the SELFY-MPI. The mean value of the SELFY-MPI was 0.131 (range: 0.0- 0.563) showing a significant correlation with age (Pearson coefficient=0.373, P<0.001). The mean value of the SELFYMPI filling time was 15 minutes (range: 5- 45 minutes) showing a significant correlation between age and filling time (Pearson coefficient=0.547, P<0.001). The SELFYMPI is an excellent self-administered tool for comprehensive self-assessment screening of community-dwelling people at risk of physical and cognitive frailty and/or socioeconomic vulnerability.