https://doi.org/10.4081/gc.2021.10007
Macroglossia reveals multiple myeloma
Submitted: 31 July 2021
Accepted: 8 November 2021
Published: 25 November 2021
Accepted: 8 November 2021
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
We present an eighty-year old man with a one year history of progressive macroglossia, dysphagia and loss of weight. He had a medical history of arterial hypertension and prostatic hypertrophy which he had under good therapeutic control. The entire tongue was swollen, had hard solidity and was slightly painful upon palpation. A tongue biopsy revealed an amyloid deposition as it coloured bright orange-red on Congo Red staining and lead us subsequently to the diagnosis of amyloidosis; then a bone marrow biopsy confirmed the diagnosis of multiple myeloma. The case was further evaluated by a multidisciplinary team who considered it appropriate to start a lowdose melphalan treatment combined with supportive care. When macroglossia in the tongue is confirmed to be amyloidosis the differential diagnosis should include systemic amyloidosis deposition and multiple myeloma.
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How to Cite
Bonvicini, M., Crapanzano, D., Fenu, S., Giordano, M., & Palleschi, L. (2021). Macroglossia reveals multiple myeloma. Geriatric Care, 7(2). https://doi.org/10.4081/gc.2021.10007
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