Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation

  • Ivo Casagranda | casagranda@libero.it Emergency Department, Santi Antonio e Biagio e Cesare Arrigo General Hospital, Alessandria, Italy.
  • Mario Cavazza Emergency Department, S. Orsola-Malpighi Hospital, Bologna, Italy.
  • Aldo Clerico Life Science Institution, S. Anna School, Pisa, Italy.
  • Marcello Galvani Emergency Department, Morgagni- Pierantoni Hospital, Forlì, Italy.
  • Filippo Ottani Emergency Department, S. Orsola-Malpighi Hospital, Bologna, .
  • Martina Zaninotto
  • Luigi M. Biasucci Department of Cardiovascular Medicine, Sacro Cuore Catholic University, Rome, Italy.
  • Gianfranco Cervellin Emergency Department, University Hospital of Parma, Italy.
  • Tiziano Lenzi Emergency Department, Santa Maria della Scaletta Civil Hospital, Imola, Italy.
  • Giuseppe Lippi Laboratory of Clinical Chemistry and Hematology, University Hospital of Parma, Italy.
  • Mario Plebani Department of Laboratory Medicine, Padua University Hospital, Italy.
  • Marco Tubaro Cardiovascular Department, San Filippo Neri Hospital, Rome, Italy.

Abstract

The purpose of this document is to develop recommendations on the use of the latest generation of cardiac troponins in emergency room settings for the diagnosis of myocardial infarction in patients with suspected acute coronary syndrome without persistent ST-segment elevation (NSTE-ACS). The main points which have been addressed reaching a consensus are: i) suitability and appropriateness of the terminology; ii) appropriateness of the request; iii) confirmation of the diagnosis of myocardial infarction (rule-in); iv) exclusion of the diagnosis of myocardial infarction (rule-out). Each point has been analyzed by taking into account the evidence presented in medical publications. Recommendations were developed using the criteria adopted by the European Society of Cardiology and the American Heart Association/American College of Cardiology. Each point of the recommendation was submitted for validation to an external audit by a Group of Experts (named above).

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Published
2013-10-03
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Issue
Section
Opinion Reports
Keywords:
acute coronary syndrome, cardiac troponin, emergency department, high-sensitivity assays, non-ST-segment elevation
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How to Cite
Casagranda, I., Cavazza, M., Clerico, A., Galvani, M., Ottani, F., Zaninotto, M., Biasucci, L., Cervellin, G., Lenzi, T., Lippi, G., Plebani, M., & Tubaro, M. (2013). Proposal for the use in emergency departments of cardiac troponins measured with the latest generation methods in patients with suspected acute coronary syndrome without persistent ST-segment elevation. Emergency Care Journal, 9(2), e14. https://doi.org/10.4081/ecj.2013.e14

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