Endoscopic removal of slow release oxycodone tablets in a case of voluntary acute poisoning

  • Sossio Serra | sossio.serra@gmail.com Emergency Department, Maurizio Bufalini Hospital, Cesena (FC), Italy.
  • Stefano Geniere Nigra Emergency Department, Maurizio Bufalini Hospital, Cesena (FC), Italy.


We describe a case of 83-years-old women admitted to the Emergency Department after massive ingestion of slow release Oxycodone pills for suicidal purpose. After gastric lavage only few tablets has been retrieved and Naloxone infusion was necessary. After 2 hours from drug ingestion Esophagogastroduodenoscopy (EGDS) was performed and a number of tablets have been removed. Intoxication symptoms completely resolved and Naloxone infusion has been stopped. The clinical courses of this intoxication suggest that the utility of EGDS to remove tablets should be considered in selected cases of drug poisoning.



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Buckley NA, Eddleston M. The revised position papers on gastric decontamination. Clin Toxicol (Phila) 2005;43:129-30. DOI: https://doi.org/10.1081/CLT-50420

Simpson SE. Pharmacobezoars described and demystified. Clin Toxicol (Phila) 2011;49:72-89. DOI: https://doi.org/10.3109/15563650.2011.559472

Hoegberg LCG, Refsgaard F, Pedersen SH et al. Potential pharmacobezoar formation of large size extended-release tablets and their dissolution – an in vitro study. Clin Toxicol (Phila) 2019;57:271-81. DOI: https://doi.org/10.1080/15563650.2018.1513138

Lapostolle F, Finot MA, Adnet F, et al. Radiopacity of clomipramine conglomerations and unsuccessful endoscopy: report of 4 cases. J Toxicol Clin Toxicol 2000;38:477-82. DOI: https://doi.org/10.1081/CLT-100102006

Saeki S, Shimoda T, Sakai H, et al. Successful treatment of theophylline toxicity by upper gastrointestinal endoscopy. Clin Toxicol (Phila) 2007;45:735.

Djogovic D, Hudson D, Jacka M. Gastric bezoar following venlafaxine overdose. Clin Toxicol 2008;46:317–9.

Höjer J, Personne M. Endoscopic removal of slow release clomipramine bezoars in two cases of acute poisoning. Clin Toxicol (Phila) 2008;46:317-9. DOI: https://doi.org/10.1080/15563650701378738

Schwerk C, Schulz M, Schwerk et al. Etilefrinhydrochloride tablet ingestion: successful therapy by endoscopic removal of tablet conglomerate. Klin Padiatr 2009;221:93-6. DOI: https://doi.org/10.1055/s-2008-1080912

Case Reports
Oxycodone, poisoning, gastric decontamination, EGDS
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How to Cite
Serra, S., & Geniere Nigra, S. (2021). Endoscopic removal of slow release oxycodone tablets in a case of voluntary acute poisoning. Emergency Care Journal, 17(1). https://doi.org/10.4081/ecj.2021.9226