https://doi.org/10.4081/ecj.2022.10468
COVID-19 and cutaneous manifestations: Two cases and a review of the literature
Submitted: 18 March 2022
Accepted: 13 April 2022
Published: 27 June 2022
Accepted: 13 April 2022
Abstract Views: 987
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
COVID-19 can affect multiple organs, including skin. A wide range of skin manifestations have been reported in literature. Six main phenotypes have been identified: i) urticarial rash, ii) confluent erythematous/maculopapular/morbilliform rash, iii) papulovesicular exanthem, iv) a chilblain-like acral pattern, v) a livedo reticularis/racemosa-like pattern, and vi) a purpuric vasculitic pattern. The pathogenetic mechanism is still not completely clear, but a role of hyperactive immune response, complement activation and microvascular injury have been postulated. The only correlation between the cutaneous phenotype and the severity of COVID-19 has been observed in the case of chilblain-like acral lesions, that is generally associated with the benign/subclinical course of COVID-19. Herein, we report two cases of SARS-CoV- 2 infection in patients who developed cutaneous manifestations that completely solved with systemic steroids and antihistamines. The first case is a female patient not vaccinated for SARS-CoV-2 with COVID-19 associated pneumonia, while the second case is a vaccinated female patient with only skin manifestations.
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How to Cite
Bastoni, D., Borio, G., Rienzo, P., Magnacavallo, A., Vercelli, A., & Poggiali, E. (2022). COVID-19 and cutaneous manifestations: Two cases and a review of the literature. Emergency Care Journal, 18(2). https://doi.org/10.4081/ecj.2022.10468
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