Tc99m-HMPAO white blood cell scintigraphy: added value of SPECT/CT for infection diagnosis in cardiothoracic surgery

  • Napoleone Prandini | s.panareo@ospfe.it Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Stefano Panareo Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Rosario Cultrera Infectious and Tropical Disease Section, University of Ferrara, Italy.
  • Chiara Peterle Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Valentina de Cristofaro Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Massimo Roncali Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Vincenzo de Biasi Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.
  • Lorenzo Badia Infectious and Tropical Disease Section, University of Ferrara, Italy.
  • Luciano Feggi Nuclear Medicine Unit, University-Hospital “S. Anna” Ferrara, Italy.

Abstract

We report a case of a woman who came to our attention because of fever and a sternal fistula draining purulent fluid. Four years before, she had undergone cardiothoracic surgery to place a patch because of a myocardial rupture. Under suspicion of a deep mediastinal infection, a Tc99m-HMPAO white blood cell (WBC) scintigraphy was performed. The use of planar imaging and single photon emission computed tomography (SPECT/CT) imaging allowed the identification of a sternal infection, which involved the anterior mediastinum up to pericardium and diaphgram. SPECT/CT led to a precise diagnosis of a thoracic infection, providing the location and extent of the disease. This turned out useful to improve therapeutic strategies.

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Published
2012-02-03
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Case Reports