https://doi.org/10.4081/ejtm.2019.8899
0
0
0
0
Smart Citations
0
0
0
0
Citing PublicationsSupportingMentioningContrasting
View Citations

See how this article has been cited at scite.ai

scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.

Neurohypophyseal hormones and skeletal muscle: a tale of two faces

Authors

Alexandra Benoni
https://orcid.org/0000-0003-3283-8660
Histology and Embryology Section, Dept. AHFOS, Sapienza University of Rome, France.
Alessandra Renzini
https://orcid.org/0000-0002-4265-7188
Histology and Embryology Section, Dept. AHFOS, Sapienza University of Rome, Italy.
Giorgia Cavioli
Histology and Embryology Section, Dept. AHFOS, Sapienza University of Rome, Italy.
Sergio Adamo
sergio.adamo@uniroma1.it
http://orcid.org/0000-0002-1409-0452
Histology and Embryology Section, Dept. AHFOS, Sapienza University of Rome, Italy.

The neurohypophyseal hormones vasopressin and oxytocin were invested, in recent years, with novel functions upon striated muscle, regulating its differentiation, trophism, and homeostasis. Recent studies highlight that these hormones not only target skeletal muscle but represent novel myokines. We discuss the possibility of exploiting the muscle hypertrophying activity of oxytocin to revert muscle atrophy, including cancer cachexia muscle wasting. Furthermore, the role of oxytocin in cardiac homeostasis and the possible role of cardiac atrophy as a concause of death in cachectic patients is discussed.

Dimensions

Altmetric

Article has an altmetric score of 1

PlumX Metrics

Downloads

Citations

Crossref
Scopus
Google Scholar
Europe PMC
Nervi C, Benedetti L, Minasi A, Molinaro M, Adamo S. Arginine-Vasopressin Induces Differentiation of Skeletal Myogenic Cells and up-Regulation of Myogenin and Myf-5. Cell Growth Differ. 1995 6 (1) 81–89.
Minotti S, Scicchitano BM, Nervi C, Scarpa S, Lucarelli M, Molinaro M, Adamo S. Vasopressin and Insulin-like Growth Factors Synergistically Induce Myogenesis in Serum-Free Medium. Cell Growth Differ. 1998 9 (2) 155–163.
Breton C, Haenggeli C, Barberis C, Heitz F, Bader CR, Bernheim L, Tribollet E. Presence of Functional Oxytocin Receptors in Cultured Human Myoblasts. J. Clin. Endocrinol. Metab. 2002 87 (3) 1415–1418. https://doi.org/10.1210/jcem.87.3.8537. DOI: https://doi.org/10.1210/jcem.87.3.8537
Costa A, Rossi E, Scicchitano BM, Coletti D, Moresi V, Adamo S. Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis. Eur. J. Transl. Myol. 2014 24 (3) 3790. https://doi.org/10.4081/ejtm.2014.3790. DOI: https://doi.org/10.4081/ejtm.2014.3790
Barberis C, Mouillac B, Durroux T. Structural Bases of Vasopressin/Oxytocin Receptor Function. J. Endocrinol. 1998 156 (2) 223–229. https://doi.org/10.1677/joe.0.1560223. DOI: https://doi.org/10.1677/joe.0.1560223
Costa A, Toschi A, Murfuni I, Pelosi L, Sica G, Adamo S, Scicchitano B. M. Local Overexpression of V1a-Vasopressin Receptor Enhances Regeneration in Tumor Necrosis Factor-Induced Muscle Atrophy. Biomed Res. Int. 2014 2014 235426. https://doi.org/10.1155/2014/235426. DOI: https://doi.org/10.1155/2014/235426
Song Z, Albers H. E. Cross-Talk among Oxytocin and Arginine-Vasopressin Receptors: Relevance for Basic and Clinical Studies of the Brain and Periphery. Front. Neuroendocrinol. 2018 51 14–24. https://doi.org/10.1016/j.yfrne.2017.10.004. DOI: https://doi.org/10.1016/j.yfrne.2017.10.004
Berio E, Divari S, Cucuzza L. S, Biolatti B, Cannizzo F. T. 17β-Estradiol Upregulates Oxytocin and the Oxytocin Receptor in C2C12 Myotubes. PeerJ 2017 2017 (3). https://doi.org/10.7717/peerj.3124. DOI: https://doi.org/10.7717/peerj.3124
Naro F, De Arcangelis V, Sette C, Ambrosio C, Komati H, Molinaro M, Adamo S, Nemoz G. A Bimodal Modulation of the CAMP Pathway Is Involved in the Control of Myogenic Differentiation in L6 Cells. J. Biol. Chem. 2003 278 (49) 49308–49315. https://doi.org/10.1074/jbc.M306941200. DOI: https://doi.org/10.1074/jbc.M306941200
Scicchitano B. M, Spath L, Musarò A, Molinaro M, Rosenthal N, Nervi C, Adamo S. Vasopressin-Dependent Myogenic Cell Differentiation Is Mediated by Both Ca2+/Calmodulin-Dependent Kinase and Calcineurin Pathways. Mol. Biol. Cell 2005 16 (8) 3632–3641. https://doi.org/10.1091/mbc.E05-01-0055. DOI: https://doi.org/10.1091/mbc.e05-01-0055
Sorrentino S, Barbiera A, Proietti G, Sica G, Adamo S, Scicchitano B. M. Inhibition of Phosphoinositide 3-Kinase/Protein Kinase B Signaling Hampers the Vasopressin-Dependent Stimulation of Myogenic Differentiation. Int. J. Mol. Sci. 2019 20 (17). https://doi.org/10.3390/ijms20174188. DOI: https://doi.org/10.3390/ijms20174188
Elabd C, Cousin W, Upadhyayula P, Chen R. Y, Chooljian M. S, Li J, Kung S, Jiang K. P, Conboy I. M. Oxytocin Is an Age-Specific Circulating Hormone That Is Necessary for Muscle Maintenance and Regeneration. Nat. Commun. 2014 5 4082. https://doi.org/10.1038/ncomms5082. DOI: https://doi.org/10.1038/ncomms5082
de Jager N, Hudson N. J, Reverter A, Wang Y. H, Nagaraju S. H, Cafe L. M, Greenwood P. L, Barnard R. T, Kongsuwan K. P, Dalrymple B. P. Chronic Exposure to Anabolic Steroids Induces the Muscle Expression of Oxytocin and a More than Fifty Fold Increase in Circulating Oxytocin in Cattle. Physiol. Genomics 2011 43 (9) 467–478. https://doi.org/10.1152/physiolgenomics.00226.2010. DOI: https://doi.org/10.1152/physiolgenomics.00226.2010
Adamo S, Pigna E, Lugarà R, Moresi V, Coletti D, Bouché M. Skeletal Muscle: A Significant Novel Neurohypophyseal Hormone-Secreting Organ. Front. Physiol. 2019 9. https://doi.org/10.3389/fphys.2018.01885. DOI: https://doi.org/10.3389/fphys.2018.01885
Pigna E, Berardi E, Aulino P, Rizzuto E, Zampieri S, Carraro U, Kern H, Merigliano S, Gruppo M, Mericskay M, et al. Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer. Sci. Rep. 2016 6. https://doi.org/10.1038/srep26991. DOI: https://doi.org/10.1038/srep26991
Moresi V, Pristerà A, Scicchitano B. M, Molinaro M, Teodori L, Sassoon D, Adamo S, Coletti D. Tumor Necrosis Factor-α Inhibition of Skeletal Muscle Regeneration Is Mediated by a Caspase-Dependent Stem Cell Response. Stem Cells 2008 26 (4) 997–1008. https://doi.org/10.1634/stemcells.2007-0493. DOI: https://doi.org/10.1634/stemcells.2007-0493
Jankowski M, Hajjar F, Al Kawas S, Mukaddam-Daher S, Hoffman G, Mccann S. M, Gutkowska J. Rat Heart: A Site of Oxytocin Production and Action. Proc. Natl. Acad. Sci. U. S. A. 1998 95 (24) 14558–14563. https://doi.org/10.1073/pnas.95.24.14558. DOI: https://doi.org/10.1073/pnas.95.24.14558
Paquin J, Danalache B. A, Jankowski M, McCann S. M, Gutkowska J. Oxytocin Induces Differentiation of P19 Embryonic Stem Cells to Cardiomyocytes. Proc. Natl. Acad. Sci. U.S.A. 2002 99 (14) 9550–9555. https://doi.org/10.1073/pnas.152302499. DOI: https://doi.org/10.1073/pnas.152302499
Florian M, Jankowski M, Gutkowska J. Oxytocin Increases Glucose Uptake in Neonatal Rat Cardiomyocytes. Endocrinology 2010 151 (2) 482–491. https://doi.org/10.1210/en.2009-0624. DOI: https://doi.org/10.1210/en.2009-0624
Jung C, Wernly B, Bjursell M, Wiseman J, Admyre T, Wikström J, Palmér M, Seeliger F, Lichtenauer M, Franz M, et al. Cardiac-Specific Overexpression of Oxytocin Receptor Leads to Cardiomyopathy in Mice. J. Card. Fail. 2018 24 (7) 470–478. https://doi.org/10.1016/j.cardfail.2018.05.004. DOI: https://doi.org/10.1016/j.cardfail.2018.05.004

Supporting Agencies

Sapienza University

How to Cite

Benoni, A., Renzini, A., Cavioli, G., & Adamo, S. (2020). Neurohypophyseal hormones and skeletal muscle: a tale of two faces. European Journal of Translational Myology, 30(1), 53–57. https://doi.org/10.4081/ejtm.2019.8899

PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.