https://doi.org/10.4081/ejtm.2022.10456
Efficacy of mechanical thrombectomy in stroke patients with large vessel involvement
Submitted: 13 March 2022
Accepted: 30 March 2022
Published: 22 June 2022
Accepted: 30 March 2022
Abstract Views: 788
PDF: 347
HTML: 5
HTML: 5
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Ischemic stroke is a common disease worldwide and leads to a significant rate of mortality and disability in patients every year, and imposes high costs on the health care system. The aim of this study was to evaluate the efficacy of the invasive method of mechanical thrombectomy for rapid intervention in ischemic stroke patients with large vessel involvement. Patients suspected of having a stroke, who were referred to Imam Hossein Hospital, were examined, and the diagnosis of stroke was confirmed. In the next stage, patients' MRS index was measured and the possibility of emergency thrombectomy was evaluated in patients. Patients who underwent thrombectomy were considered as the case group and the other patients were contemplated as the control group; then, the cases of the two groups were evaluated and compared. The mean age of patients was 66.63 ± 12.26 years. the use of emergency thrombectomy in the study group significantly reduced the MRS index of patients after 90 days (p <0.001), while a significant increase in the mean scores of the MRS index was seen in patients receiving pharmacological treatments. Also, there was no significant difference in terms of gender between the group of patients undergoing thrombectomy and the group receiving other treatments (p = 0.375). Emergency mechanical thrombectomy significantly reduces disability in stroke patients in the long term and can be a good alternative to conventional drug treatments.
Zhang S, Hao Y, Tian X, Zi W, Wang H, Yang D, Zhang M, Zhang X, Bai Y, Li Z, Sun B, Li S, Fan X, Liu X, Xu G. Safety of Intra-Arterial Tirofiban Administration in Ischemic Stroke Patients after Unsuccessful Mechanical Thrombectomy. J Vasc Interv Radiol. 2019 Feb;30(2):141-147.e1. Epub 2019 Jan 2. PMID: 30611627.
DOI: https://doi.org/10.1016/j.jvir.2018.08.021
Cheng Z, Geng X, Gao J, Hussain M, Moon SJ, Du H, Ding Y. Intravenous Administration of Standard Dose Tirofiban after Mechanical Arterial Recanalization is Safe and Relatively Effective in Acute Ischemic Stroke. Aging Dis. 2019 Oct 1;10(5):1049-1057. PMID: 31595202; PMCID: PMC6764734.
DOI: https://doi.org/10.14336/AD.2018.0922
Hackshaw A, Morris JK, Boniface S, Tang JL, Milenkovi? D. Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports. BMJ. 2018 Jan 24;360:j5855. Erratum in: BMJ. 2018 Apr 11;361:k1611. Erratum in: BMJ. 2018 Nov 28;363:k5035. PMID: 29367388; PMCID: PMC5781309.
DOI: https://doi.org/10.1136/bmj.j5855
Ciaccio EJ, Lewis SK, Biviano AB, Iyer V, Garan H, Green PH. Cardiovascular involvement in celiac disease. World J Cardiol. 2017 Aug 26;9(8):652-666. PMID: 28932354; PMCID: PMC5583538.
DOI: https://doi.org/10.4330/wjc.v9.i8.652
Abbott AL, Silvestrini M, Topakian R, Golledge J, Brunser AM, de Borst GJ, Harbaugh RE, Doubal FN, Rundek T, Thapar A, Davies AH, Kam A, Wardlaw JM. Optimizing the Definitions of Stroke, Transient Ischemic Attack, and Infarction for Research and Application in Clinical Practice. Front Neurol. 2017 Oct 18;8:537. PMID: 29104559; PMCID: PMC5654955.
DOI: https://doi.org/10.3389/fneur.2017.00537
Guercini F, Acciarresi M, Agnelli G, Paciaroni M. Cryptogenic stroke: time to determine aetiology. J Thromb Haemost. 2008 Apr;6(4):549-54. Epub 2008 Jan 15. PMID: 18208534.
DOI: https://doi.org/10.1111/j.1538-7836.2008.02903.x
Hackam DG, Hegele RA. Cholesterol Lowering and Prevention of Stroke. Stroke. 2019 Feb;50(2):537-541. PMID: 30602355.
DOI: https://doi.org/10.1161/STROKEAHA.118.023167
Shiber JR, Fontane E, Adewale A. Stroke registry: hemorrhagic vs ischemic strokes. Am J Emerg Med. 2010 Mar;28(3):331-3. PMID: 20223391.
DOI: https://doi.org/10.1016/j.ajem.2008.10.026
Lapergue B, Labreuche J, Blanc R, Barreau X, Berge J, Consoli A, Rodesch G, Saleme S, Costalat V, Bracard S, Desal H, Duhamel A, Baffert S, Mazighi M, Gory B, Turjman F, Piotin M; ASTER Trial Investigators. First-line use of contact aspiration for thrombectomy versus a stent retriever for recanalization in acute cerebral infarction: The randomized ASTER study protocol. Int J Stroke. 2018 Jan;13(1):87-95. Epub 2017 Jun 8. PMID: 28592218.
DOI: https://doi.org/10.1177/1747493017711948
Wahlgren N, Moreira T, Michel P, Steiner T, Jansen O, Cognard C, Mattle HP, van Zwam W, Holmin S, Tatlisumak T, Petersson J, Caso V, Hacke W, Mazighi M, Arnold M, Fischer U, Szikora I, Pierot L, Fiehler J, Gralla J, Fazekas F, Lees KR; ESO-KSU, ESO, ESMINT, ESNR and EAN. Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int J Stroke. 2016 Jan;11(1):134-47. PMID: 26763029.
DOI: https://doi.org/10.1177/1747493015609778
Delgado Almandoz JE, Kayan Y, Young ML, Fease JL, Scholz JM, Milner AM, Hehr TH, Roohani P, Mulder M, Tarrel RM. Comparison of clinical outcomes in patients with acute ischemic strokes treated with mechanical thrombectomy using either Solumbra or ADAPT techniques. J Neurointerv Surg. 2016 Nov;8(11):1123-1128. Epub 2015 Dec 14. PMID: 26667250.
DOI: https://doi.org/10.1136/neurintsurg-2015-012122
Hackshaw A, Morris JK, Boniface S, Tang JL, Milenkovi? D. Low cigarette consumption and risk of coronary heart disease and stroke: meta-analysis of 141 cohort studies in 55 study reports. BMJ. 2018 Jan 24;360:j5855. Erratum in: BMJ. 2018 Apr 11;361:k1611. Erratum in: BMJ. 2018 Nov 28;363:k5035. PMID: 29367388; PMCID: PMC5781309.
DOI: https://doi.org/10.1136/bmj.j5855
Renieri L, Saia V, Pereira VM, Pracucci G, Limbucci N, Nappini S, Tyrrell PN, Arba F, Nencini P, Inzitari D, Giorgianni A, Natrella M, Menozzi R, Scoditti U, Mangiafico S, Danilo Toni; Italian Registry of Endovascular Treatment in Acute Stroke. Mechanical thrombectomy in patients with proximal occlusions and low NIHSS: Results from a large prospective registry. J Stroke Cerebrovasc Dis. 2020 Oct;29(10):105091. Epub 2020 Jul 30. PMID: 32912516.
DOI: https://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105091
Brinjikji W, Pasternak J, Murad MH, Cloft HJ, Welch TL, Kallmes DF, Rabinstein AA. Anesthesia-Related Outcomes for Endovascular Stroke Revascularization: A Systematic Review and Meta-Analysis. Stroke. 2017 Oct;48(10):2784-2791. Epub 2017 Sep 13. PMID: 28904228.
DOI: https://doi.org/10.1161/STROKEAHA.117.017786
Löwhagen Hendén P, Rentzos A, Karlsson JE, Rosengren L, Leiram B, Sundeman H, Dunker D, Schnabel K, Wikholm G, Hellström M, Ricksten SE. General Anesthesia Versus Conscious Sedation for Endovascular Treatment of Acute Ischemic Stroke: The AnStroke Trial (Anesthesia During Stroke). Stroke. 2017 Jun;48(6):1601-1607. PMID: 28522637.
DOI: https://doi.org/10.1161/STROKEAHA.117.016554
Kissela BM, Khoury JC, Alwell K, Moomaw CJ, Woo D, Adeoye O, Flaherty ML, Khatri P, Ferioli S, De Los Rios La Rosa F, Broderick JP, Kleindorfer DO. Age at stroke: temporal trends in stroke incidence in a large, biracial population. Neurology. 2012 Oct 23;79(17):1781-7. Epub 2012 Oct 10. PMID: 23054237; PMCID: PMC3475622.
DOI: https://doi.org/10.1212/WNL.0b013e318270401d
Qureshi AI, Singh B, Huang W, Du Z, Lobanova I, Liaqat J, Siddiq F. Mechanical Thrombectomy in Acute Ischemic Stroke Patients Performed Within and Outside Clinical Trials in the United States. Neurosurgery. 2020 Jan 1;86(1):E2-E8. PMID: 31670379.
DOI: https://doi.org/10.1093/neuros/nyz359
Kamal N, Majmundar N, Damadora N, El-Ghanem M, Nuoman R, Keller IA, Schonfeld S, Rybinnik I, Gupta G, Roychowdry S, Al-Mufti F. Mechanical thrombectomy - is time still brain? The DAWN of a new era. Br J Neurosurg. 2018 Jun;32(3):245-249. Epub 2018 Feb 8. PMID: 29417839.
DOI: https://doi.org/10.1080/02688697.2018.1426726
Lambrinos A, Schaink AK, Dhalla I, Krings T, Casaubon LK, Sikich N, Lum C, Bharatha A, Pereira VM, Stotts G, Saposnik G, Kelloway L, Xie X, Hill MD. Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review. Can J Neurol Sci. 2016 Jul;43(4):455-60. Epub 2016 Apr 13. PMID: 27071728; PMCID: PMC4926268.
DOI: https://doi.org/10.1017/cjn.2016.30
Wahlgren N, Moreira T, Michel P, Steiner T, Jansen O, Cognard C, Mattle HP, van Zwam W, Holmin S, Tatlisumak T, Petersson J, Caso V, Hacke W, Mazighi M, Arnold M, Fischer U, Szikora I, Pierot L, Fiehler J, Gralla J, Fazekas F, Lees KR; ESO-KSU, ESO, ESMINT, ESNR and EAN. Mechanical thrombectomy in acute ischemic stroke: Consensus statement by ESO-Karolinska Stroke Update 2014/2015, supported by ESO, ESMINT, ESNR and EAN. Int J Stroke. 2016 Jan;11(1):134-47. PMID: 26763029.
DOI: https://doi.org/10.1177/1747493015609778
Jovin TG, Chamorro A, Cobo E, de Miquel MA, Molina CA, Rovira A, San Román L, Serena J, Abilleira S, Ribó M, Millán M, Urra X, Cardona P, López-Cancio E, Tomasello A, Castaño C, Blasco J, Aja L, Dorado L, Quesada H, Rubiera M, Hernandez-Pérez M, Goyal M, Demchuk AM, von Kummer R, Gallofré M, Dávalos A; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015 Jun 11;372(24):2296-306. Epub 2015 Apr 17. PMID: 25882510.
DOI: https://doi.org/10.1056/NEJMoa1503780
How to Cite
Aghamiri, S. H., Mansouri, B., Mehrpour, M., Karani, S. M. H., Ghaffari, M., Lima, B. S., & Komlakh, K. . (2022). Efficacy of mechanical thrombectomy in stroke patients with large vessel involvement. European Journal of Translational Myology, 32(2). https://doi.org/10.4081/ejtm.2022.10456
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.