TY - JOUR AU - Silva, Gilmar Pereira AU - Carneiro, Fabiana Pirani AU - Grangeiro, Vitor Pereira Xavier PY - 2018/03/31 Y2 - 2024/03/28 TI - Seminal transferrin in the seminal quality evaluation of hemodialytic patients JF - Archivio Italiano di Urologia e Andrologia JA - Arch Ital Urol Androl VL - 90 IS - 1 SE - Original Papers - Andrology DO - 10.4081/aiua.2018.1.49 UR - https://www.pagepressjournals.org/aiua/article/view/aiua.2018.1.49 SP - 49-53 AB - Objective: to verify the association between seminal quality and seminal transferrin (ST) level and fertility index in patients undergoing chronic hemodialysis (CH). <br />Material and methods: This is a cross-sectional study in a group of 60 men (case) undergoing CH for more than 6 months, and a group of 30 healthy men (control), aged 18-60 years, without clinical or laboratory signs of infection/inflammation. Spermiogram was performed, fertility index (FI) was calculated and ST and sex hormones (SH) levels were measured, including follicle-stimulating hormone, luteinizing hormone, total testosterone, and prolactin. <br />Results: All individuals were eugonadal. No differences for age (49.47 ± 5.56, 47.90 ± 6.2, p = 0.22) were observed between cases and controls, whereas there were significant differences between the individuals in the case and control groups with respect to the mean FI (p = 0.000), seminal parameters (SP) (p = 0.000), and ST levels (40.12 ± 08.25 vs 73.32 ± 06.8, p = 0.000). ST levels were correlated with FI (r = 0.787, p = 0.00) and SP (motility: r = 0.857, p = 0.000; vitality: r = 0.551, p = 0.000; density: r = 0.850, p = 0.000; normal morphology: r = 0.386, p = 0.000). Linear regression model showed relationship of ST levels with total sperm motility (R2 = 0.701; p = 0.000) and and FI (R2 = 0.569; p = 0.000). <br />Conclusions: Our results suggest that seminal quality is associated with ST levels and FI and that it can be used the initial investigation of subfertility/infertility of patients undergoing chronic hemodialysis.. ER -