Premature Ejaculation patients and their partners: arriving at a clinical profile for a real optimization of the treatment.

  • Paolo Verze Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Roberto La Rocca | robertolarocca87@gmail.com Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Lorenzo Spirito Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Gianluigi Califano Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Luca Venturino Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Luigi Napolitano Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Antonio Cardi Department of Urology, San Giovanni Hospital, Rome, Italy.
  • Davide Arcaniolo Department of Urology, Vanvitelli University, Naples, Italy.
  • Claudia Rosati Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Alessandro Palmieri Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.
  • Vincenzo Mirone Department of Neurosciences, Reproductive Sciences and Odontostomatology, Urology Section, University of Naples Federico II, Naples, Italy.

Abstract

The aim of the study is to extrapolate clinical features of Premature Ejaculation (PE) patients and female partners of men affected with PE, in order to get a profile that can be of assistance for physicians within the dynamics of a couple, one of which is a PE patient. An observational, non-interventional, cross-sectional epidemiological study entitled IPER (Italian Premature Ejaculation Research) was conducted and included two different cohorts of subjects that were randomly sampled from a patient dataset of selected General Practitioners: 1. IPER-M sub-cohort (1.104 subjects) was made of male subjects in which they were then distinguished patients with or without PE based on the score of the PEDT questionnaire; IPER-F sub-cohort (1.109 subjects) was made of female subjects from an independent sample of women (therefore not the partners of the IPER-M males) in which they then distinguished those partners of a male subject with PE or not. In addition to an identical general questionnaire to explore demographic aspects and habits, each subcohort was then evaluated using validated questionnaires. No differences were noted between PE+/PE- patients in terms of alcohol consumption, smoking habits, physical activity nor stress condition in everyday life, employment, socio-economic class and marital status. While the prevalence of PE proportionally increased with age, excluding the 50-59 and 70-80 years decades, in the IPER-M group an overall statistically significant difference for the mean age between the PE+ and PE- groups (p = 0.002) was detected, but without reaching any difference amongst the different age classes in the IPER-F group. The PE+ patients reported a significantly lower frequency rate of sexual intercourse, worse QoL (p = 0.006 and p < 0.0001, respectively), and increased anxiety status (p < 0.0001 for both subgroups). This study shows that, rather than talking with a patient affected by PE it would be advisable to introduce the concept of couple counseling with the person patient and his partner, because it is only through classification of both partners as one couple and a full understanding of their mutual sexual experience that PE treatment can be optimized and its results measured accurately.

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References

Hatzimouratidis K, Giuliano F, Moncada I, et al. EAU Guidelineson Erectile Dysfunction, Premature Ejaculation, Penile Curvature and Priapism http://uroweb.org/guideline/male-sexual-dysfunction/ LAST UPDATE MARCH 2018.

Althof SE, McMahon CG, Waldinger MD, et al. An Update of the International Society of Sexual Medicine's Guidelines for the diagnosis and treatment of Premature Ejaculation(PE) J Sex Med. 2014;2:60-90. DOI: https://doi.org/10.1002/sm2.28

Symonds T, Roblin D, Hart K, Althof S How does premature ejaculation impact a man’s life? J Sex Marital Ther. 2003; 29:361-70. DOI: https://doi.org/10.1080/00926230390224738

Rust J, Golombok S, Collier J. Marital problems and sexual dysfunction: How are they related? Br J Psychiatry. 1988; 152:629-31. DOI: https://doi.org/10.1192/bjp.152.5.629

Moore JT, Goldstein Y. Sexual problems among family medicine patients. J Fam Pract. 1980; 10:243-7.

Rowland DL, Cooper SE, Schneider M. Defining premature ejaculation for experimental and clinical investigations. Arch Sex Behav 2001; 30:235-253. DOI: https://doi.org/10.1023/A:1002714812709

Limoncin E, Tomassetti M, Gravina GL, et al. Premature ejaculation results in female sexual distress: standardization and validation of a new diagnostic tool for sexual distress. J Urol. 2013;189:1830-5. DOI: https://doi.org/10.1016/j.juro.2012.11.007

Hartmann U, Schedlowski M, Kruger TH. Cognitive and partnerrelated factors in rapid ejaculation: Differences between dysfunctional and functional men. World J Urol. 2005; 23:93-101. DOI: https://doi.org/10.1007/s00345-004-0490-0

Abdo CH. The impact of ejaculatory dysfunction upon the sufferer and his partner. Transl Androl Urol. 2016; 5:460-9. DOI: https://doi.org/10.21037/tau.2016.05.08

Verze P, Arcaniolo D, Palmieri A, et al. Premature ejaculation among Italian men: prevalence and clinical correlates from an observational, non-Interventional, cross-sectional, epidemiological study (IPER). Sex Med. 2018;6:193-202. DOI: https://doi.org/10.1016/j.esxm.2018.04.005

Verze P, Arcaniolo D, Imbimbo C, et al. General and sex profile of women with partner affected by premature ejaculation: results of a large observational, non-interventional, cross-sectional, epidemiological study (IPER-F). Andrology. 2018; 6:714-719. DOI: https://doi.org/10.1111/andr.12545

Laumann EO, Paik A, Rosen RC. Sexual dysfunction in the United States: prevalence and predictors. JAMA, 1999;281:537. DOI: https://doi.org/10.1001/jama.281.6.537

Ventus D, Jern P. Lifestyle factors and premature ejaculation: are physical exercise, alcohol consumption, and body mass index associated with premature ejaculation and comorbid erectile problems? J Sex Med. 2016. 13:1482. DOI: https://doi.org/10.1016/j.jsxm.2016.08.007

Dunn KM, Croft PR, Hackett GI. Association of sexual problems with social, psychological, and physical problems in men and women: a cross sectional population survey. J Epidemiol Community Health. 1999; 53:144. DOI: https://doi.org/10.1136/jech.53.3.144

Xia Y, Li J, Shan G, et al. Relationship between premature ejaculation and depression: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore), 2016; 95:e4620. DOI: https://doi.org/10.1097/MD.0000000000004620

Porst H, Montorsi F, Rosen RC, et al. The premature ejaculation prevalence and attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Eur Urol. 2007; 51:816-23.

Rowland D, Perelman M, Althof S, et al. Self-reported premature ejaculation and aspects of sexual functioning and satisfaction. J Sex Med. 2004; 1:225. DOI: https://doi.org/10.1111/j.1743-6109.2004.04033.x

Capece M, La Rocca R, Mirone V, et al. A systematic review on ischemic priapism and immediate implantation: do we need more data? Sexual Medicine Reviews. 2019; 7:530-534. DOI: https://doi.org/10.1016/j.sxmr.2018.10.007

Laumann EO, Nicolosi A, Glasser DB, et al. Sexual problems among women and men aged 40-80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors. Int J Impot Res. 2005; 17:39. DOI: https://doi.org/10.1038/sj.ijir.3901250

Porst H, Montorsi F, Rosen RC, et al. The Premature Ejaculation Prevalence and Attitudes (PEPA) survey: prevalence, comorbidities, and professional help-seeking. Eur Urol. 2007; 51:816. DOI: https://doi.org/10.1016/j.eururo.2006.07.004

Cormio L, Massenio P, La Rocca R, et al. The combination of dapoxetine and behavioral treatment provides better results than dapoxetine alone in the management of patients with lifelong premature ejaculation. J Sex Med. 2015; 12:1609. DOI: https://doi.org/10.1111/jsm.12925

Published
2021-03-18
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Original Papers - Andrology
Keywords:
Premature ejaculation, Partner, Profile, Clinical
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How to Cite
Verze, P., La Rocca, R., Spirito, L., Califano, G., Venturino, L., Napolitano, L., Cardi, A., Arcaniolo, D., Rosati, C., Palmieri, A., & Mirone, V. (2021). Premature Ejaculation patients and their partners: arriving at a clinical profile for a real optimization of the treatment. Archivio Italiano Di Urologia E Andrologia, 93(1), 42-47. https://doi.org/10.4081/aiua.2021.1.42