Could pollen extract in association with vitamins be favorable in the reduction of chronic prostatic inflammation? A case-series analysis

  • Michele Zazzara | michele.zazzara@gmail.com Urology Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.
  • Arjan Nazaraj Urology Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.
  • Ottavio Colamonico Urology Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.
  • Marcella Mastromauro Pathological Anatomy Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.
  • Giuseppe Cardo Urology Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.
  • Giuseppe Mario Ludovico Urology Department, Ospedale Generale Regionale “F. Miulli", Acquaviva delle Fonti (BA), Italy.

Abstract

The aim of the present case-series analysis was to assess the safety and efficacy of pollen extract in association with vitamins in order to reduce the chronic prostatic inflammation in patients with class IV chronic prostatitis (CP). Nineteen non-consecutive patients performed a prostate biopsy for a suspect of prostate cancer. The biopsy histopathological examination showed a class IV CP, in presence of mild/moderate/high degree of inflammation, in association with an extensive (multiple biopsy sites, i.e., ≥ 3) high-grade prostatic intraepithelial neoplasia PIN (HGPIN) and/or atypical small acinar proliferation (ASAP). According to EAU Prostate Cancer Guidelines prostate biopsy was repeated after 6 months, because of the presence of extensive HGPIN or ASAP. Oral administration of pollen extract in association with vitamins (two capsules every 24 h) was prescribed until the repeat biopsy. Repeat biopsy histopathological examination showed, in 13 patients (68.4%), a lower degree of inflammation (absent/mild/moderate).

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Published
2019-07-02
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Section
Original Papers - Prostate
Keywords:
Prostate, Phytotherapeutics, Benign prostatic hyperplasia
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How to Cite
Zazzara, M., Nazaraj, A., Colamonico, O., Mastromauro, M., Cardo, G., & Ludovico, G. M. (2019). Could pollen extract in association with vitamins be favorable in the reduction of chronic prostatic inflammation? A case-series analysis. Archivio Italiano Di Urologia E Andrologia, 91(2). https://doi.org/10.4081/aiua.2019.2.84