Blastoid variant of mantle cell lymphoma of the female urethra mimicking a caruncle: A rare but highly aggressive subtype case with literature review

  • Franco Palmisano | franco.palmisano@hotmail.it Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Urology, Milan; University of Milan, Italy.
  • Vito Lorusso Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Urology, Milan; University of Milan, Italy.
  • Matteo Giulio Spinelli Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Urology, Milan, Italy.
  • Paolo Guido Dell'Orto Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Urology, Milan, Italy.
  • Emanuele Montanari Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Department of Urology, Milan; University of Milan, Italy.

Abstract

Primary urethral lymphoma is a rare entity without a standardized treatment protocol. We report a case of an elderly woman presenting with a caruncle associated with vaginal spotting and intermittent dysuria. She underwent surgical excision of the lesion. Histological analysis revealed a blastoid variant of mantle cell lymphoma, a previously unreported subtype. The patient received chlorambucil assisting a rapid local disease progression. She died of disseminated disease 6 months after diagnosis. A review of the lymphomas of the urethra is included.

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Published
2019-03-29
Info
Issue
Section
Case Reports
Keywords:
Caruncle, lymphoma, urethra, genitourinary, mantle cell lymphoma, blastic variant
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How to Cite
Palmisano, F., Lorusso, V., Spinelli, M., Dell’Orto, P., & Montanari, E. (2019). Blastoid variant of mantle cell lymphoma of the female urethra mimicking a caruncle: A rare but highly aggressive subtype case with literature review. Archivio Italiano Di Urologia E Andrologia, 91(1), 49-50. https://doi.org/10.4081/aiua.2019.1.49