Skin flap squamous cell carcinoma developed after urethroplasty

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Danilo Abate
Giuseppe Giusti
Nicola Caria *
Giuseppe De Vita
Marco Lucci Chiarissi
Antonello De Lisa
(*) Corresponding Author:
Nicola Caria |


Objectives: To describe our experience in diagnosis and treatment of urethral carcinoma following urethroplasty with a Orandi penile skin flap.
Material and methods: Our patient underwent to Orandi penile skin flap urethroplasty then developed a urethral epidermoid carcinoma on the flap approximately 15 years later. We treated this case with a partial penectomy surgery and perineostomy. Surgery was followed by chemotherapy with cisplatin and 5-fluorouracil. The progression of the disease led to a salvage surgery of total penectomy and asportation of testicles and scrotum.
Results: Despite the success of the surgery, the disease progressed and three months after the last surgical operation the patient died.
Conclusions: Urethral carcinoma on skin flap is a rare complication of the urethroplasty surgery but with severe consequences, so we recommend to undertake a long-term urological follow up in patients undergone such kind of surgery.

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