Malignant priapism due to penile metastases: Case series and literature review

  • Francesco De Luca | francescodeluca10@gmail.com St Peter's Andrology and the Insitute of Urology, University College London Hospital, London, United Kingdom.
  • Evangelos Zacharakis Department of Urology, Guy’s Hospital, Kings College London, United Kingdom.
  • Majed Shabbir Department of Urology, Guy’s Hospital, Kings College London, United Kingdom.
  • Angela Maurizi Department of Gynecologic-Obstetric Sciences and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • Emy Manzi Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Rome, Italy.
  • Antonio Zanghì General Surgery and Breast Unit, Department of Surgery University of Catania, Catania, Italy.
  • Carlo De Dominicis Department of Gynecologic-Obstetric Sciences and Urological Sciences, Sapienza University of Rome, Rome, Italy.
  • David Ralph St Peter's Andrology and the Insitute of Urology, University College London Hospital, London, United Kingdom.

Abstract

Malignant priapism secondary to penile metastases is a rare condition. This term was originally used by Peacock in 1938 to describe a condition of painful induration and erection of the penis due to metastatic infiltration by a neoplasm. In the current literature there are 512 case reports. The primary tumor sites are bladder, prostate and rectum. The treatment has only palliative intent and consists of local tumor excision, penectomy, radiotherapy and chemotherapy. We present one case of malignant priapism originated from prostate cancer, and two from urothelial carcinoma of the bladder. Different approaches in diagnosis and therapy were performed. The entire three patient reported a relief of the pain following the treatment, with an improvement of their quality of life, even though it was only temporary as a palliative. Malignant priapism is a rare medical emergency. Penile/pelvis magnetic resonance imaging (MRI) scan and corporal biopsies are considered an effective method of diagnosis of the primary organ site.

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Published
2016-07-04
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Issue
Section
Case Reports - Andrology
Supporting Agencies
none
Keywords:
Priapism, Tumour, Metastases
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How to Cite
De Luca, F., Zacharakis, E., Shabbir, M., Maurizi, A., Manzi, E., Zanghì, A., De Dominicis, C., & Ralph, D. (2016). Malignant priapism due to penile metastases: Case series and literature review. Archivio Italiano Di Urologia E Andrologia, 88(2), 150-152. https://doi.org/10.4081/aiua.2016.2.150