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Localised prostate cancer and hemophilia A (AHA): Case report and management of the disease

Francesco Celestino, Cristian Verri, Francesco De Carlo, Savino Mauro Di Stasi
  • Francesco Celestino
    Urologic Oncology Unit, Policlinico Casilino, Rome, Italy | frapichi@libero.it
  • Cristian Verri
    Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy
  • Francesco De Carlo
    Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy
  • Savino Mauro Di Stasi
    Department of Experimental Medicine and Surgery, Tor Vergata University, Rome, Italy

Abstract

Acquired Hemophilia A (AHA) is a rare bleeding diathesis characterized by the development of autoantibodies against factor VIII (FVIII). About half of the cases are idiopathic and the other half are associated with autoimmune diseases, postpartum problems, infections, inflammatory bowel disease, drugs, lymphoproliferative disorders or solid tumors . AHA is associated with malignancies in 7-15% of cases. We report a case of AHA in a 65 year old patient with prostatic carcinoma, who underwent retropubic radical prostatectomy (RP).

Keywords

Activated partial thromboplastin time; Factor VIII; Hemophilia A; Prostate cancer; Radical prostatectomy

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Submitted: 2014-10-10 11:31:42
Published: 2014-09-30 00:00:00
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Copyright (c) 2014 Francesco Celestino, Cristian Verri, Francesco De Carlo, Savino Mauro Di Stasi

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