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Serenoa repens extract additionally to quinolones in the treatment of chronic bacterial prostatitis. The preliminary results of a long term observational study

Konstantinos Stamatiou, Nikolaos Pierris
  • Konstantinos Stamatiou
    Urology Department, Tzaneio Hospital, Pireas, Greece |
  • Nikolaos Pierris
    Urology Department, Tzaneio Hospital, Pireas, Greece


Introduction: Chronic prostatitis displays a variety of symptoms (mainly local pain exhibiting variability in origin and intensity). The purpose of this article is to briefly present the preliminary results of our study examining the role of phytotherapeutic agents in the treatment of chronic prostatitis patients. Materials and methods: The study included in total fifty-six consecutive patients who visited the outpatient department. Subjects were randomized into two groups. Subjects in the first group (28 patients) received prulifloxacin 600 mg for 15 days, while subjects in the second group (28 patients) received prulifloxacin 600 mg for 15 days and Serenoa repens extract for 8 weeks. The response was tested using laboratory and clinical criteria. Results: We found statistically significant differences between the two groups regarding pain regression and no statistically significant regarding bacterial eradication. Moreover however while sexual dysfunction improvement was equally achieved in both groups, improvement of urinary symptoms was more evident in the 2nd group especially after the completion of the antibiotic treatment. Conclusions: Serenoa repens extract for 8 weeks seems to improve prostatitis related pain. Further randomized, placebo-controlled studies are needed to substantiate safer conclusions.


Chronic prostatitis, Phytotherapeutics; Quinolones; Pain; Serenoa repens

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Submitted: 2014-01-02 16:21:04
Published: 2013-12-31 00:00:00
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Copyright (c) 2013 Konstantinos Stamatiou, Nikolaos Pierris

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