https://doi.org/10.4081/aiua.2020.4.328
Observational study on the effects of a topical formulation in patients with premature ejaculation
Published: December 18, 2020
Abstract Views: 975
PDF: 557
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
Premature ejaculation (PE) has been defined as the inability to control or delay ejaculation, resulting in dissatisfaction or distress of the patient. Although PE is the most frequent sexual dysfunction, it is still underdiagnosed. An accurate clinical history is the best diagnostic approach that, in the majority of cases, is enough to differentiate between primary and acquired PE. Nowadays, treatment is not curative but is effective in increasing the intravaginal ejaculatory latency time (IELT), improving the sexual satisfaction of the couple [...].
Parnham A, Serefoglu EC. Classification and definition of premature ejaculation. Transl Androl Urol. 2016; 5:416-23.
DOI: https://doi.org/10.21037/tau.2016.05.16
Hu QB, Zhang D, Ma L, Ng DM, Haleem M, Ma Q. Progresses in pharmaceutical and surgical management of premature ejaculation. Chin Med J (Engl). 2019;132:2362-2372
DOI: https://doi.org/10.1097/CM9.0000000000000433
Althof SE. Patient reported outcomes in the assessment of premature ejaculation. Transl Androl Urol. 2016;5(4):470-4.
DOI: https://doi.org/10.21037/tau.2016.05.04
Rosen RC, Riley A, Wagner G, et al. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49:822-30.
DOI: https://doi.org/10.1016/S0090-4295(97)00238-0
Bryant BP, Mezine I. Alkylamides that produce tingling paresthesia activate tactile and thermal trigeminal neurons. 1999. 25;842(2):452-60.
DOI: https://doi.org/10.1016/S0006-8993(99)01878-8
Lennertz RC, Makoto Tsunozaki, Bautista DM, Stucky CL. Physiological basis of tingling paresthesia evoked by hydroxy-alpha-sanshool. J Neurosci. 2010. 24;30(12):4353-61.
DOI: https://doi.org/10.1523/JNEUROSCI.4666-09.2010
Nejad SM, Özgüneş H, Başaran N. Pharmacological and Toxicological Properties of Eugenol. Turk J Pharm Sci. 2017;14(2):201-206.
DOI: https://doi.org/10.4274/tjps.62207
Wang ZJ, Tabakoff B, Levinson SR, Heinbockel T. Inhibition of Nav1.7 channels by methyl eugenol as a mechanism underlying its antinociceptive and anesthetic actions. Acta Pharmacol Sin. 2015 Jul;36(7):791-9.
DOI: https://doi.org/10.1038/aps.2015.26
How to Cite
Quarto, G., Castaldo, L. ., Grimaldi, G., Izzo, A., Muscariello, R., & Perdonà, S. (2020). Observational study on the effects of a topical formulation in patients with premature ejaculation. Archivio Italiano Di Urologia E Andrologia, 92(4). https://doi.org/10.4081/aiua.2020.4.328
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.