A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation

  • Salvatore Sansalone | salvatore.sansalone@yahoo.it Department of Experimental Medicine and Surgery, University Tor Vergata, Rome, Italy.
  • Giorgio Ivan Russo Department of Urology, University of Catania, Catania, Italy.
  • Nicola Mondaini Urologic Unit, Santa Maria Annunziata Hospital, Bagno a Ripoli, Florence, Italy.
  • Francesco Cantiello Urology Unit, Magna Graecia University of Catanzaro, Italy.
  • Gabriele Antonini Department of Urology, "Sapienza" Rome University, Rome, Italy.
  • Tommaso Cai Department of Urology, Santa Chiara Regional Hospital, Trento, Italy.

Abstract

Objective: The management of patient affected by premature ejaculation (PE) is nowadays not highly satisfactory. Here, we aimed to evaluate the tolerability and efficacy of a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts in order to improve sexual quality of life in patients with premature ejaculation. Materials and methods: All patients attending to 5 urological centers from January 2015 to March 2015, due to premature ejaculation were enrolled in this study. At the enrolment visit, all subjects underwent self-administered IIEF-5, Male Sexual Health Questionnaire-Ejaculation Disorder (MSHQEjD), PEDT and IELTS (calculated as mean from that perceived by partner and that perceived by patient) and underwent urological visit and laboratory examinations. All patients received one tablet per day of a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts for 3 months (Group A). After 3 months all patients underwent follow-up visit with the same investigations that have been carried out in the enrolment visit. The results were compared with a cohort of patients enrolled in the same period in another urological center and considered as a control group (Group B). All patients in the control group underwent counseling and sexual behavioral treatment without any pharmacological compound. Results: At the follow-up analysis, significant changes in terms of IELT in the Group A (mean difference: 31.90; p < 0.05) at 3 months and versus Group B at the intergroup analysis (mean difference: 30.30; p < 0.05) were reported. In the group A, significant differences from baseline to last follow- up were observed relative to IIEF-5 (mean difference: 1.04; p < 0.05), PEDT (mean difference: -2.57; p < 0.05) and FSH (mean difference: -16.46; p < 0.05). Conclusion: In conclusion, patients affected by PE may significantly benefit from oral therapy with a combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts in terms of IELT and PEDT scores improvement.

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Published
2016-10-05
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Original Papers - Andrological Sciences
Keywords:
Premature ejaculation, Erectile dysfunction, Tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica.
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How to Cite
Sansalone, S., Russo, G., Mondaini, N., Cantiello, F., Antonini, G., & Cai, T. (2016). A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation. Archivio Italiano Di Urologia E Andrologia, 88(3), 171-176. https://doi.org/10.4081/aiua.2016.3.171

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